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For older adults

Fall Risk Up With Initiation, Intensification of HTN Meds

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Short-term fall risk up during 15 days after initiation, intensification of antihypertensive medication
Patients with bipolar disorder taking lithium have lower rates of self-harm and unintentional injury compared to those taking other mood stabilizers

Fewer Self-Injury Events With Lithium for Bipolar Disorder

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Patients on one of the alternative mood stabilizers were 40 percent more likely to harm themselves
For premenopausal women with breast cancer

Two Years of Tamoxifen Offers Long-Term Survival Benefit

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Survival benefit for premenopausal women with estrogen receptor-positive primary breast cancer
Nilotinib is associated with scurvy

Nilotinib Associated With Case of Scurvy

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Drug appears to affect cutaneous metabolism; patient improved with ascorbic acid supplements
The synthetic prostaglandin E1 analogue misoprostol has known severe side effects and should be considered in cases of postpartum hyperthermia

Misoprostol Should Be Considered in Postpartum Hyperthermia

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Report of 21-year-old with severe hyperthermia, rigors, tachycardia, transient encephalopathy
The endothelin-1 blocker macitentan does not reduce the number of new digital ulcers over 16 weeks among patients with systemic sclerosis and active ischemic digital ulcers

Macitentan Doesn’t Reduce Number of New Digital Ulcers

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Findings over 16 weeks among patients with systemic sclerosis and active ischemic digital ulcers
Low doses of ketamine may quickly reduce suicidal thoughts in patients with treatment-resistant depression

Ketamine May Ease Suicidal Thoughts in Major Depression

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Small study found that the drug worked quickly in patients with treatment-resistant depression
For patients with lipodystrophy

Metreleptin Ups Resting-State Connectivity in Lipodystrophy

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Significant increases in hypothalamus; insula, superior temporal gyrus; medial prefrontal cortex
Genetic variants have been identified in psoriasis patients that correlate with anti-tumor necrosis factor-α treatment response

Genetic Variants ID Treatment Response in Psoriasis

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Ten SNPs presented that correlate with treatment responses to anti-TNF-α agents
For patients with compensated hepatitis C virus cirrhosis

Survival for HCV Cirrhosis, SVR Same As General Population

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Findings in patients with compensated HCV cirrhosis who achieve SVR on interferon-based regimen