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For patients with type 2 diabetes

Exenatide Twice Daily Deemed Efficacious Across BMI Ranges

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Significant weight loss with exenatide across BMI ranges; weight increased with comparators
For healthy females

Progesterone Attenuates Drug-Induced QT Interval Lengthening

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Findings in healthy females who received progesterone or placebo for seven days
For acute myocardial infarction survivors

ACEI/ARBs Up AMI Outcomes Regardless of Renal Status

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Treatment linked to improved long-term survival, regardless of underlying kidney function
For patients with type 1 diabetes mellitus

Liraglutide Is Not Justified for All Patients With T1DM

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Addition of 1.2 and 1.8 mg liraglutide linked to modest reduction of weekly mean glucose levels
For patients with Child-Pugh B and C

Propranolol Use Tied to Increased Mortality in Child-Pugh B, C

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Propranolol use beyond six months linked to increased mortality in Child-Pugh C with ascites
For patients with heart failure with reduced ejection fraction

Sacubitril-Valsartan May Be Cost-Effective Option in HFrEF

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More costly than enalapril but more effective over a lifetime in heart failure with reduced ejection fraction
For patients undergoing endoscopic retrograde cholangiopancreatography (ERCP)

Rectal Indomethacin Doesn’t Prevent Post-ERCP Pancreatitis

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Indomethacin no benefit for patients undergoing endoscopic retrograde cholangiopancreatography
Despite initial concern from early studies

Lamotrigine in Pregnancy Not Linked to Certain Birth Defects

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Excess risk of orofacial cleft estimated to be less than one in every 550 exposed babies
For patients with worsening heart failure

Diuretic Dose Not Linked to Outcome in Heart Failure

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In multivariate analysis, no correlation seen for patients with worsening heart failure
For patients with primary hyperparathyroidism

Surgery Cuts Fracture Risk in Primary Hyperparathyroidism

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Reduced fracture risk for surgery; bisphosphonate treatment no better than observation