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For patients undergoing transcatheter aortic valve replacement

High Rate of Cerebral Embolization During TAVR

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No significant differences in cerebral embolization measures during TAVR with bivalirudin vs. heparin
For patients receiving an everolimus-eluting stent implantation

Adverse Events Not Up With Six Months of DAPT

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Comparable results for 12-month DAPT among patients receiving everolimus-eluting stents
Use of pembrolizumab (Keytruda) in advanced melanoma is extending survival for many and even curing some

ASCO: Pembrolizumab Improves Survival in Melanoma

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Three-year overall survival rate of 40 percent; median overall survival of 24.4 months
Hydroxyurea may help preserve lung function in children with sickle cell disease

ATS: Hydroxyurea Can Up Lung Function in Sickle Cell Disease

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Drug slowed down the annual decline children had been showing before starting treatment
Dose and duration of therapy are associated with mortality for new antipsychotic users

For New Antipsychotic Users, Dose, Duration Impact Mortality

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Lower mortality risk for modified standardized daily dose of 1 or less versus greater than 1
Hospitalists report limited success and satisfaction for management of acute exacerbations of chronic pain with opioids

Hospitalists Need Strategies for Providing Adequate Pain Relief

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Hospitalists report limited success for management of acute exacerbations of chronic pain with opioids
For patients with a history of chronic obstructive pulmonary disease exacerbations

ATS: Indacaterol-Glycopyrronium Cuts COPD Exacerbations

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More effective than salmeterol-fluticasone for patients with history of COPD exacerbations
For older adults

Fall Risk Up With Initiation, Intensification of HTN Meds

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Short-term fall risk up during 15 days after initiation, intensification of antihypertensive medication
Patients with bipolar disorder taking lithium have lower rates of self-harm and unintentional injury compared to those taking other mood stabilizers

Fewer Self-Injury Events With Lithium for Bipolar Disorder

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Patients on one of the alternative mood stabilizers were 40 percent more likely to harm themselves
For premenopausal women with breast cancer

Two Years of Tamoxifen Offers Long-Term Survival Benefit

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Survival benefit for premenopausal women with estrogen receptor-positive primary breast cancer