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For patients with type 2 diabetes taking metformin

Liraglutide Tops Lixisenatide As Add-On to Metformin in T2DM

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Greater reduction in hemoglobin A1c, greater reduction in fasting plasma glucose with liraglutide
In patients with early breast cancer

Candesartan Doesn’t Prevent Trastuzumab Cardiotoxicity

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Cumulative incidence of cardiac events not significantly different with candesartan, placebo
Misuse of opioids by American adults more than doubled from the early 2000s to 2013

Misuse of Opioids Doubled in the United States Over a Decade

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Over 4 percent of adults reported nonmedical use of drugs like OxyContin in 2012 to 2013
For women undergoing abdominal hysterectomy

Superior Hypogastric Plexus Block Beneficial After Hysterectomy

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Ropivacaine linked to reduced postoperative opioid consumption, pain versus placebo
For East Asian patients with type 2 diabetes

50 Percent Insulin Lispro/Insulin Lispro Protamine Efficacious

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More effective than LM25 in certain dietary conditions, including with increased carbohydrate
Vitamin K antagonists are well tolerated and have a minimal effect on quality of life

Vitamin K Antagonists Appear to Be Well Tolerated

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Study Short-Form 36 scores improved during initial 3 months of treatment to level of general population
For patients with heart failure due to light-chain amyloidosis

Three-Drug Tx Ups Survival in Light-Chain Amyloidosis

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Bortezomib, dexamethasone, alkylating agent treatment ups survival for patients with heart failure
Dulaglutide and glargine in combination with prandial lispro are associated with a similar percentage of time spent in the normoglycemic range

Dulaglutide, Glargine Plus Lispro Improve Glycemic Control

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Dulaglutide and glargine plus lispro result in similar proportion of glucose values in normoglycemic range
The dipeptidyl peptidase-4 inhibitors vildagliptin and sitagliptin have similar effects on incretin hormone secretion

Vildagliptin, Sitagliptin Have Similar Effects on Incretin

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Inter-individual variability seen in L-cell feedback induced by DPP-4 inhibitors
For patients with fibromyalgia

IV Lidocaine Has No Meaningful Impact in Fibromyalgia

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No clinical manifestations for combination of lidocaine for four weeks with amitriptyline