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Among adults with septic shock

Vasopressin Doesn’t Cut Kidney Failure-Free Days in Septic Shock

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No improvement in kidney failure-free days versus norepinephrine in adults with septic shock
Government spending on compounded drugs has skyrocketed

Spending on Compounded Drugs Skyrocketing

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Number of Medicare beneficiaries getting compounded drugs up 281 percent since 2006
Opioid users may be misusing and abusing gabapentin

Some Opioid Users May Be Taking Gabapentin Without an Rx

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Findings reveal need for more robust testing
For patients with allergic rhinitis

House Dust Mite Immunotherapy Effective for Allergic Rhinitis

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Large randomized trial in Japan shows improvement in Average Adjusted Symptom Score
Topical application of BRAF inhibitors may accelerate healing of skin wounds

BRAF Inhibitors May Accelerate Wound Healing

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Topical application with vemurafenib accelerated wound healing via paradoxical MAPK activation
Biosimilar and reference tumor necrosis factor-α inhibitors appear to be appropriately interchangeable

Biosimilar and Reference TNF-α Inhibitors Comparable

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Pharmacokinetic parameters of both versions within the prespecified equivalence margin
Liraglutide (Victoza) doesn't appear to improve heart function in patients with advanced heart failure

Liraglutide Not Beneficial in Advanced Heart Failure

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No difference in heart function, disease stability or in rates of mortality, rehospitalization
For patients with metastatic melanoma

Add-On Local Peripheral Tx Beneficial in Metastatic Melanoma

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Addition to ipilimumab has beneficial effect on overall survival even after adjustment
The magnitude of the risk of adverse outcomes associated with metamizole use varies in different studies

Variation in Risk of Adverse Outcomes With Metamizole

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Relative risk estimates vary from 1.5 to 40.2 for agranulocytosis, from 1.5 to 2.7 for upper GI bleed
Deprescribing of antipsychotics in long-term care residents with previous behavioral and psychological symptoms of dementia is feasible

AAIC: Deprescribing Antipsychotics Feasible in Elderly

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Staff training can help eliminate inappropriate practices in nursing homes, study says