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In patients with high-risk relapsed/refractory acute myelogenous leukemia (AML) or untreated AML unfit for intensive chemotherapy

Venetoclax Monotherapy Active in AML With Adverse Features

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Overall response rate 19%; additional 19% have antileukemic activity without meeting IWG criteria
Alitretinoin treatment aids in normalizing expression of barrier genes and proteins in patients with chronic hand eczema

Alitretinoin Cuts Chronic Hand Eczema Severity

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Treatment seems to normalize expression of skin barrier genes, proteins
For women undergoing urogynecologic surgery

Polyethylene Glycol 3350 Doesn’t Cut Time to Bowel Movement

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Addition of PEG3350 to docusate sodium cuts use of additional laxatives, increases drug adherence
Intravenous immunoglobulin is increasingly being used for interstitial lung disease

IV Immunoglobulin Use Up in Interstitial Lung Disease

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No studies support use of IVIg in ILD, but increasingly being used off-label for refractory cases
Mitomycin C and 5-flurouracil improve outcomes following Ahmed glaucoma valve implantation

Antifibrotics Up Outcomes After Ahmed Glaucoma Valve Implant

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Adjuvant treatment following AGV implantation improves treatment success, cuts hypertensive phase
At least one San Francisco-area individual died and eight more were treated in the emergency department in late 2015 after taking counterfeit alprazolam (Xanax) tablets that had been cut with fentanyl

Counterfeit Alprazolam Cut With Fentanyl Can Be Fatal

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One person died, eight were sickened when illicit pills circulated in San Francisco
Elbasvir-grazoprevir is effective for patients with chronic hepatitis C virus receiving opioid-agonist therapy

Elbasvir-Grazoprevir Effective for HCV With Opioid-Agonist Tx

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High rates of sustained virologic response at 12 wks, regardless of drug use at baseline or during tx
For patients with type 1 diabetes

Addition of Dapagliflozin Improves Glycemia in T1DM

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Improvements in glycated hemoglobin, weight loss with addition of dapagliflozin to insulin, liraglutide
Limited access to pharmacies may be one reason hospital readmission is more common among older patients in rural

Readmission Rates Up for Seniors With Low Access to Pharmacies

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Problem is acute in small, rural areas of Oregon, researchers find
Targeted therapies that do not contain erlotinib can be beneficial for patients with KRAS-mutated advanced non-small-cell lung cancer

Targeted Therapies Beneficial in KRAS-Mutated NSCLC

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Improved progression-free survival for patients treated with therapy not containing erlotinib