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Use of antipsychotics in pregnancy does not appear to increase the risk for congenital malformations

Antipsychotic Use Doesn’t Up Congenital Malformations

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No increased risk for congenital malformation or cardiac malformation with typical, atypical APs
Clinicians might be overprescribing β-blocker medications to heart patients

β-Blockers Not Always Indicated for PCI Patients

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Findings in patients with stable angina without history of MI or heart failure undergoing elective PCI
For patients with acute coronary syndrome

Thrombocytopenia Up With Use of Phosphate-Buffered Tirofiban

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Relative risk for thrombocytopenia not increased with use of citrate-buffered tirofiban
A large randomized trial is being developed to compare the effectiveness of hydrochlorothiazide with chlorthalidone in Veterans Affairs patients

Large Trial Proposed to Compare HCTZ, Chlorthalidone

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Researchers plan randomized study to compare hydrochlorothiazide, chlorthalidone
Arhalofenate (800 mg) is safe and significantly decreases gout flares compared to allopurinol (300 mg)

Arhalofenate Beats Allopurinol for Gout Flares

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Arhalofenate at an 800 mg dosage seems safe and well tolerated
Interferon-free direct-acting antiviral therapy is beneficial for hepatitis C virus-associated mixed cryoglobulinemia vasculitis

Interferon-Free, Tailored Tx Beneficial in HCV-Associated MC

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Guideline-tailored therapy highly effective, safe for hepatitis C virus-associated mixed cryoglobulinemia
The interaction between the organic cation transporter 1 and the serotonin reuptake transporter seems to play a role in metformin intolerance

OCT1, SERT Genes Play Role in Metformin Intolerance

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Intolerance up with low-expressing SERT S* alleles; multiplicative interaction for OCT1, SERT genotypes
Liraglutide added to capped insulin is associated with reductions in glycated hemoglobin

Liraglutide Added to Capped Insulin Reduces Hemoglobin A1c

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Liraglutide also significantly reduces mean body weight, daily insulin dose; increases quality of life
Twenty-four weeks of empagliflozin + metformin correlates with a significantly greater reduction in hemoglobin A1c compared with once-daily empagliflozin or twice-daily metformin

Greater Drop in Hemoglobin A1c With Empagliflozin + Metformin

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Greater reductions in HbA1c, weight compared to empagliflozin or metformin alone
Patients who receive early treatment for symptoms consistent with the onset of multiple sclerosis are about one-third less likely to eventually be diagnosed with multiple sclerosis than participants whose treatment is delayed

Long-Term Benefit Seen for Early Treatment of MS Symptoms

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Industry-funded study also found therapy doubled time until a relapse occurred