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Psychotherapy, Meds Effective to Treat Depression in Patients With Heart Failure

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Both behavioral activation psychotherapy and antidepressant medication management reduce depressive symptoms by about 50 percent

Higher Use of Any Rx Medications Seen Years Before IBD Diagnosis

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Findings strongest for Crohn disease with ties to multisystem organ involvement

Simnotrelvir Shortens Time to Resolution of Symptoms in COVID-19

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On day 5, the decrease in viral load from baseline was greater in the simnotrelvir group versus placebo group

FDA Approves Casgevy to Treat Beta-Thalassemia

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Casgevy is the first CRISPR-based medicine to be approved for use in the United States

New Rx for Schedule-II Stimulants for ADHD Increased During Pandemic

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No significant changes seen in new prescriptions for antidepressants, benzodiazepines, or buprenorphine for opioid use disorder

Cannabis Does Not Impact Nonmedical Opioid Use in Opioid Use Disorder

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No association seen between cannabis use and nonmedical opioid use in those receiving pharmacotherapies for OUD

Liraglutide Exerts Weight Loss-Independent, GLP-1R-Dependent Effects

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Prior to weight loss, liraglutide improves insulin sensitivity; reductions in fasting and postprandial glucose also seen

Combo of PDE5i, Nitrates Increases Cardiovascular Morbidity, Mortality in Stable CAD

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Increased risk for cardiovascular morbidity and mortality seen with PDE5i use for erectile dysfunction in men with CAD

Gabapentinoids Linked to Increased Risk for Severe Exacerbation in COPD

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Compared with matched nonusers, gabapentinoid users have increased risk across indications of epilepsy, neuropathic pain, other chronic pain

FDA Finds No Evidence Linking Wegovy, Ozempic to Suicidal Behaviors

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However, the agency noted officials cannot rule out that 'a small risk may exist,' and it will continue to investigate