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Bioactive Retinol Efficacious for Improving Signs of Photoaging

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Improvement seen in all signs of photoaging as early as week 4 and through 12 weeks, with no major irritation

One in Seven Drug Supply Chain Issue Reports Tied to Drug Shortages

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Supply disruptions increased for drugs with and without reports at the start of the COVID-19 pandemic

Vaginal Delivery Similar With Vaginal, Oral Misoprostol Protocols

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Oxytocin was required less often before delivery for women receiving vaginal versus oral misoprostol

Etidronate Beneficial for Arterial Calcification Due to CD73 Deficiency

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Etidronate seems to slow progression of further vascular calcification

ACC: Ticagrelor Monotherapy Cuts Bleeding Risk in Acute Coronary Syndrome

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Lower risk for clinically relevant bleeding seen in acute coronary syndrome, with no increase in risk for MACCE

ACC: Empagliflozin Cuts Heart Failure Hospitalization Risk After AMI

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Lower risks for first heart failure hospitalization, total heart failure hospitalization seen with empagliflozin

AACR: Little Benefit Seen for Cancer Drugs Given Accelerated Approval

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Fewer than half of cancer drugs granted accelerated approval demonstrate clinical benefit

AACR: Cadonilimab Plus Chemo Beneficial for Gastric Adenocarcinoma

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Improved overall survival, progression-free survival seen, including among patients with low PD-L1 expression

Biosimilar Biologics Do Not Always Reduce Out-of-Pocket Costs

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Findings seen in large study of commercially insured outpatients examining seven biologics, before and after biosimilar availability

Use of Medications for Alcohol Use Disorder Improves Outcomes

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Reduction seen in incidence of composite outcome of all-cause mortality, return to hospital with MAUD initiation at discharge