Tag: Prescription Drugs
Glucarpidase Improves Outcomes in Patients With Methotrexate-Induced Kidney Toxicity
Glucarpidase associated with 2.70-fold increased odds of kidney recovery in methotrexate-acute kidney injury
Adjuvant Trastuzumab Emtansine Improves Overall Survival in HER2+ Breast Cancer
T-DM1 sustained the improvement in invasive disease-free survival over trastuzumab in HER2-positive early breast cancer
Differences Exist in Precision Oncology Drug Eligibility Among Patient Ancestral Groups
Patients of African ancestry had the lowest precision oncology drug-based clinical actionability from 2019 onward
MEK Inhibition Beneficial for Children With Subset of Severe Hypertrophic Cardiomyopathy
Decrease in mortality, morbidity seen with trametinib for children with RASopathy-associated hypertrophic cardiomyopathy
Polypill Treatment Offers High Value in Low-Income, Underserved Population
Polypill treatment estimated at $8,560 per QALY gained compared with usual care and had high value in 99 percent of simulations
Some Maternal Medications Lower Levels of Protein, Fat in Breastmilk
Significantly lower protein levels seen with SSRIs and steroids; mean fat lower for mothers with other anti-inflammatory drugs
Talquetamab Plus Teclistamab Shows Promise in Multiple Myeloma
Grade 3 or 4 adverse events occurred in 96 percent of patients; grade 3 or 4 infections occurred in 64 percent
Eight in 10 Infants Received RSV Protection in the 2023 to 2024 Season
Findings seen within a single health care system during the early period of availability
Denosumab Increases Cardiovascular Risk in Dialysis-Dependent Patients
Denosumab has greater preventive effect on fractures, but increased risk for MACE compared with oral bisphosphonates
Incident Gabapentin Use Not Linked to Increase in Falls Versus Duloxetine
Findings seen in older adults with diabetic neuropathy, postherpetic neuralgia, or fibromyalgia