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Early Dapagliflozin Does Not Impact Diuretic Efficiency in Acute Heart Failure

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Loop diuretic doses reduced and median 24-hour natriuresis and urine output improved in association with dapagliflozin

Rapid Procedure Noninferior for Extended-Release Naltrexone Initiation

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Rapid procedure noninferior to standard procedure for successful initiation of extended-release naltrexone

Upping Dose May Aid Smoking Cessation After Initial Treatment Failure

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Benefit seen with additional six weeks of treatment after six weeks of initial failure with varenicline or nicotine replacement

Elimination of Buprenorphine Waiver Had Moderate Effect

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Significant increase seen in monthly number of buprenorphine prescribers, but modest increase seen in number of patients receiving buprenorphine

Seven Percent of Outpatients Experience One or More Adverse Event

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Overall, 23.2 percent of adverse events are preventable; 17.2 percent are serious

Chronic Hepatitis B Virus Is Undertreated

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Findings seen in global study of patients in nine countries

Cabozantinib Promising for Metastatic Pheochromocytomas, Paragangliomas

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Overall response rate was 25.0 percent in phase 2 study involving 17 patients

Cabozantinib Promising for Advanced Adrenocortical Carcinoma

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Promising efficacy seen with a manageable safety profile in phase 2 study involving 18 patients

AI May Be Useful in Polypharmacy Management

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ChatGPT deprescribing decisions varied along activities of daily living status, cardiovascular disease history, and medication type

Antihypertensive Meds Initiation Linked to Fractures in Nursing Home Seniors

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Antihypertensive medication initiation also linked to higher risk for severe falls requiring hospitalization, ED visits