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Once-Daily TAS-303 Superior to Placebo for Stress Urinary Incontinence

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TAS-303 had superior efficacy to placebo at week 12 and was associated with only mild or moderate adverse events

Blinatumomab + Chemo Ups Survival in B-Cell Precursor Acute Lymphoblastic Leukemia

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Improved overall survival and three-year relapse-free survival seen with blinatumomab plus chemo for adult patients

Hydroxychloroquine Safe, Effective Treatment for Anogenital Lichen Sclerosus

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Response rate higher for anogenital versus extragenital lichen sclerosus

Declines Seen in Medical, Nonmedical Use of Prescription Meds Among Teens

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Increase seen in prevalence of teens who reported that it would probably be impossible to obtain prescription meds for nonmedical use

Exposure to Hydroxyurea Does Not Impact Ovarian Reserve in Sickle Cell

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For girls with sickle cell disease, density of growing follicles was marginally lower in hydroxyurea group after adjustment for age

Digoxin, Beta-Blockers Have Equivalent Effects on Heart Rate in A-Fib

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Wearable device data could predict New York Heart Association functional class similarly to clinical measures and six-minute walk test

Efanesoctocog Alfa Prophylaxis Beneficial for Children With Hemophilia A

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Authors note high sustained factor VIII activity and protection against bleeding episodes, including bleeding into joints

Risankizumab Noninferior, Superior to Ustekinumab for Crohn Disease

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Risankizumab noninferior for clinical remission at week 24, superior for endoscopic remission at week 48

Ofatumumab Effective for MS Across Racial, Ethnic Subgroups

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Ofatumumab is more effective than teriflunomide for relapsing multiple sclerosis across subgroups

Aging Into Medicare Tied to Higher Drug Costs for People With Diabetes

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Quarterly out-of-pocket costs increased by approximately $23 on average after age 65 years