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Tag: Premature Birth

Women on antiepileptic drugs during pregnancy for epilepsy or other indications are at increased risk of giving birth to premature and small-for-gestational-age infants

Risk of Prematurity, SGA Up for Women on Antiepileptic Drugs

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Increased risk for women on AEDs for epilepsy or other indications; risk varies with drug used
Several genetic variants are associated with gestational duration and preterm birth

Genetic Variants Tied to Preterm Birth, Gestational Length

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Four loci found to be significantly associated with gestational duration, three with preterm birth
During the past two decades

Increase in Survival Without Severe Disability for Preemies

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However, children born preterm still have high risk for developmental delay
Insomnia and sleep apnea during pregnancy are associated with significantly increased risk of preterm birth

Maternal Sleep Disorders Increase Risk of Preterm Birth

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Odds of preterm birth higher among women with insomnia or sleep apnea during pregnancy
Parents of adults who very preterm or very low birth weight at birth have similar quality of life to that of parents of term adults

QOL Not Impaired for Parents of Now-Adults Born Very Preterm

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Childhood mental health, peer relationships predict parental QOL for children born VP, VLBW
From 1991 to 2005

Benefit of Newer NICU Ventilation Strategies Questioned

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No significant decline seen in oxygen dependence at 36 weeks or improvement in lung function at age 8
Children born extremely preterm have reduced rod and cone function compared with children born at term

Rod, Cone Function Down for Children Born Extremely Preterm

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Preterm group had significantly lower amplitudes of combined rod and cone, isolated cone responses
For preterm infants

Iodide Supplementation No Benefit for Preemies

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No significant difference in neurodevelopmental status at 2 years for infants with iodide vs. placebo
For extremely preterm infants

Hydrocortisone Tx Doesn’t Impair Neurodevelopment in Preemies

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No statistically significant difference in neurodevelopment at 2 with hydrocortisone, placebo
Higher prepregnancy body mass index is associated with increased risk of preterm delivery in the absence of chronic diseases

Maternal Obesity Without Chronic Illness Ups Preterm Delivery Risk

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Risk of extremely preterm delivery varies by parity