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Tag: Pre-eclampsia

Women with a history of hypertensive disorders of pregnancy have a greater long-term risk for stroke that is reduced by aspirin use

Hypertensive Disorders of Pregnancy Tied to Stroke Risk

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However, primary preventive treatment with aspirin may cut long-term risk for stroke
Preeclampsia seems to be associated with an increased risk for dementia

Preeclampsia Tied to Increased Risk for Vascular Dementia

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Hazard ratios moderately attenuated with adjustment for diabetes, hypertension, CVD
Supplementation with folic acid beyond the first trimester does not prevent preeclampsia among high-risk women

Folic Acid Past First Trimester Doesn’t Prevent Preeclampsia

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Supplementation beyond first trimester does not reduce risk of preeclampsia in high-risk women
Vitamin D status does not have a causal effect on gestational hypertension or preeclampsia

No Causal Effect of 25(OH)D on Gestational HTN, Preeclampsia

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No significant correlations identified in one-sample or two-sample mendelian randomization analyses
First-trimester screening for preeclampsia can be improved using a combination of maternal factors and biomarkers

Maternal Factors, Biomarkers Improve Preeclampsia Screening

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Performance of screening as recommended by NICE guidelines was poor, with low compliance
Use of antihypertensive treatments during delivery hospitalizations in women with preeclampsia has increased since 2006

Rise in Use of Antihypertensives in Delivery With Preeclampsia

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Treatment trend associated with decreased risk of maternal stroke over same time period
More than 40 percent of women with severe preeclampsia have hypertension one year after delivery

Hypertension Common One Year After Severe Preeclampsia

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Based on ambulatory BP monitoring, 41.5 percent of women had hypertension one year after delivery
Psychostimulant use during pregnancy is associated with a small increased relative risk of preeclampsia and preterm birth

Psychostimulant Use Tied to Placental Complications

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Small increased relative risk of preeclampsia, preterm birth; absolute risk increases are small
The relative risk of a seizure disorder after eclampsia is higher than that of women unaffected by eclampsia but remains extremely low

Eclampsia Tied to Increased Relative Risk of Seizure Disorder

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However, the risk remains extremely low, at 4.58/10,000 person-years
Rates of preeclampsia continue to increase in the United States

Study Quantifies Health and Economic Burden of Preeclampsia

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Preeclampsia rates have risen steadily since the 1980s