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Tag: Pneumonia

The first prescription of an antibiotic that the average U.S. adult with pneumonia receives is now ineffective in about a quarter of cases

ATS: First Abx Rx Doesn’t Work for ~25% of Pneumonia Cases

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One in four adult patients do not respond to initial prescription of antibiotic treatment
Neutrophil-to-lymphocyte ratio can predict 30-day mortality for elderly adults with community-acquired pneumonia

Neutrophil-to-Lymphocyte Ratio Predicts Mortality in CAP

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NLR predicts 30-day mortality for elderly adults admitted with community-acquired pneumonia
For patients with dementia

Proton Pump Inhibitor Use Ups Pneumonia Risk in Dementia

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Independent risk factors for pneumonia include age, male gender, underlying cerebrovascular disease
Introduction of seven-valent and 13-valent pneumococcal conjugate vaccine correlated with a reduction in Streptococcus pneumoniae bacteremia

Post-PCV13 Drop in Streptococcus pneumoniae Bacteremia

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As pneumococcal rates dropped, rates of E. coli, Salmonella spp, Staphylococcus aureus increased
For children with community-acquired pneumonia

Nonclinical Factors Drive Antibiotic Choice in Pediatric CAP

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Age, previous antibiotic receipt, private insurance up odds of macrolide versus amoxicillin receipt
Inhaled corticosteroids do not appear to be associated with the risk of pneumonia in children with asthma

Inhaled Corticosteroids Not Linked to Pneumonia in Children

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No increased risk of pneumonia; no link for ICS with risk of pharyngitis, otitis media, sinusitis
Among adults with diagnosed diabetes

CDC Finds Vaccination Coverage Varies for Adults With Diabetes

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Influenza vaccination coverage more prevalent than pneumococcal or hepatitis B vaccination
For children with complicated pneumonia

IV, Oral Antibiotics Compared for Complicated Pneumonia

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No difference in post-discharge treatment failure; more complications, adverse drug events for PICC
It may be safe to switch from broad- to narrow-spectrum antibiotic coverage once hospitalized patients with healthcare-associated pneumonia reach clinical stability

Narrow-Spectrum Abx Feasible in Healthcare-Associated Pneumonia

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Findings among clinically stable inpatients with healthcare-associated pneumonia
Antimicrobials are often prescribed for a longer duration than recommended in guidelines

Antimicrobial Tx Duration Often Exceeds Recommendations

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Antimicrobials often prescribed for a longer duration than guideline recommendations