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Tag: Peripheral Artery Disease

Both duration and intensity of smoking have a long-term impact on the risk for three major atherosclerotic diseases: peripheral artery disease

Smoking Has Long-Term Impact on Peripheral Artery Disease Risk

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Risk for peripheral artery disease remains 30 years after smoking cessation
Microvascular disease increases the risk for amputation alone and in combination with peripheral artery disease

Risk for Leg Amputation Higher With Microvascular Disease

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Risk higher regardless of microvascular disease location or other blood vessel conditions
For patients with intermittent claudication

Adherence Superior for Alternative Exercise Modalities in PAD

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Completion and adherence rates improved for alternative exercise versus traditional walking
Major bleeding occurs in about 4 percent of lower-extremity peripheral vascular intervention procedures

Study Looks at Risk for Bleeding in Percutaneous Tx of PAD

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Major bleeding in lower-extremity peripheral vascular interventions tied to higher in-hospital mortality
Heat therapy can improve functional ability and also has the potential to be an effective cardiovascular conditioning tool for people with peripheral arterial disease

Hot Water Therapy Aids Patients With Peripheral Arterial Disease

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Small study shows it improves functional ability, has potential for cardiovascular conditioning
A preliminary analysis has revealed a "potentially concerning signal" of increased long-term mortality risk with paclitaxel-coated products indicated for peripheral arterial disease

FDA Issues Update on Mortality Risk With Paclitaxel-Coated Products

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Preliminary analyses revealed approximately 50 percent increased risk at five-year follow-up
Exposure to paclitaxel in drug-coated balloons used in procedures for the treatment of symptomatic femoropopliteal peripheral arterial disease is not associated with mortality

Paclitaxel Exposure in Vascular Device Not Linked to Mortality

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No deaths thought to be related to use of paclitaxel drug-coated balloons for vascular procedures in PAD
Cigarette smoking is associated with measures of subclinical peripheral artery disease in African-Americans

Smoking Tied to Peripheral Artery Disease in African-Americans

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Current smokers had increased risk for measures of subclinical peripheral artery disease
The U.S. Food and Drug Administration alerted health care providers on Thursday that the agency is investigating the use of paclitaxel-coated balloons and paclitaxel-eluting stents to treat peripheral arterial disease in the femoropopliteal artery because of a potentially increased mortality risk in the long term.

FDA Investigating Paclitaxel-Coated Balloons, Paclitaxel-Eluting Stents

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Investigation triggered by meta-analysis showing possible increased mortality in PAD patients at 2 years
Appropriate use criteria have been developed for peripheral artery intervention in peripheral artery disease

Appropriate Use Criteria Released for Peripheral Artery Intervention

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Guideline-directed medical therapy, lifestyle and risk factor modification are cornerstones of therapy