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Tag: Parkinson’s

α-Synuclein Seed Amplification Assay Classifies Parkinson Disease

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High sensitivity and specificity seen for Parkinson disease; α-synuclein SAA can also detect prodromal individuals

Racial, Ethnic Minorities With Parkinson Disease Have Worse HRQoL

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Cognition partially mediated the association between race/ethnicity and 39-item Parkinson disease questionnaire scores

Unilateral Pallidal Ultrasound Ablation Beneficial in Parkinson Disease

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Authors note a significantly reduced levodopa-induced dyskinesia and motor severity score opposite to the treated side

Antiepileptic Drugs Tied to Incident Parkinson Disease

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Magnitude of the association increased with the number of antiepileptic drugs prescribed

Natural Environments May Cut Hospitalization for Patients With Neurodegenerative Diseases

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Normalized difference vegetation index negatively associated with hospitalization for Alzheimer disease and related dementia, Parkinson disease

Deferiprone Not Beneficial for Newly Diagnosed Parkinson Disease

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Greater decrease seen in nigrostriatal iron content with deferiprone, but more patients have symptom progression leading to initiation of dopaminergic therapy

Parkinsonism, Parkinson Disease Risk Up With Bilateral Oophorectomy Before 43

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Risk increased in premenopausal women undergoing oophorectomy for benign indication before age 43 years

ENT-01 Safe, Improves Constipation in Patients With Parkinson Disease

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Improvement seen in weekly complete spontaneous bowel movement rate and in secondary end points

Weight Loss in Early Parkinson Linked to Cognitive Decline

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Patients with weight loss in first year have significantly faster decline in Montreal Cognitive Assessment scores

Hospital-Treated Infections Earlier in Life Tied to Alzheimer, Parkinson Disease Risk

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Association found for Alzheimer and Parkinson disease cases diagnosed before 60 years of age