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Tag: Parkinson’s

Cerebral hypoperfusion contributes to dizziness in patients with Parkinson's disease

Dizziness in Parkinson’s May Be Due to Cerebral Hypoperfusion

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Transcranial Doppler during head-up tilting useful for evaluating dizziness
Individuals with hepatitis B and hepatitis C have increased rates of subsequent Parkinson's disease

Hepatitis B, C Linked to Higher Subsequent Rates of Parkinson’s

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Increased rates of subsequent Parkinson's for those with hepatitis B, C, but not autoimmune hepatitis
For patients with Parkinson's disease

Regular Exercise Slows Decline Even in Advanced Parkinson’s Dz

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Slower declines in health-related quality of life, mobility for increasing exercise by 30 minutes/week
Xadago (safinamide) tablets have been approved by the U.S. Food and Drug Administration as an add-on drug to treat Parkinson's patients who take levodopa or carbidopa but experience "off" episodes.

FDA Approves New Parkinson’s Add-On Drug Xadago

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To help prevent 'off' episodes among users of levodopa/carbidopa
Measuring blood neurofilament light chain levels may help distinguish Parkinson's disease from atypical parkinsonian disorders

Diagnostic Potential for Blood-Based NfL in Parkinson’s Disease

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Blood neurofilament light chain levels may prove useful in both primary care and specialized clinics
Cognitive co-activation is associated with a significantly smaller levodopa effect on resting tremor in Parkinson's disease

Cognitive Stress Reduces Levodopa Effect in Parkinson’s

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Levodopa effect significantly smaller during cognitive co-activation than during rest
For patients with Parkinson's disease receiving levodopa therapy and experiencing end-of-dose motor fluctuations

Opicapone As Levodopa Adjunct Cuts Motor Fluctuations in PD

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In Parkinson's disease, 50-mg/day opicapone linked to significant reduction in mean daily off-time
A gene mutation has been identified that could be associated with early-onset Parkinson's disease

Gene Mutation Linked to Early-Onset Parkinson’s Disease

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Mutated GCH1 gene tied to 23 percent increased risk of Parkinson's; symptoms five years earlier
An inhaled version of the Parkinson's drug levodopa can help when patients experience symptoms between doses of the pill form of the medication

Inhaled Levodopa May Rapidly Relieve Parkinson’s Symptoms

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Levodopa pill can wear off, but a powdered version can help patients during off periods
Parkinson's disease patients with glucocerebrosidase gene mutations have increased risk for dementia and death

Dementia, Mortality Risk Up for GBA Carriers With Parkinson’s

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Mortality risk remained greater in carriers after introduction of dementia as time-dependent covariate