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Tag: Parkinson’s

The office-based

Montreal Parkinson Risk of Dementia Scale Deemed Accurate

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All eight items of office-based scale independently predict development of dementia in Parkinson's
Alpha-synuclein levels in tears differ significantly for patients with Parkinson's disease and healthy controls

AAN: Alpha-Synuclein Levels in Tears May Help ID Parkinson’s

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PD patients have significantly decreased total alpha-synuclein in tears compared with healthy controls
For patients with dementia with Lewy bodies

Adjunct Zonisamide Beneficial in Dementia With Lewy Bodies

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Zonisamide as an adjunct to levodopa improves parkinsonism without worsening cognitive function
Training with a cable-driven robot is associated with improved response to perturbations and increased gait stability among patients with Parkinson's disease

Robot Training Improves Gait Stability in Parkinson’s

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Improvements seen in response to perturbations while walking and in gait stability
Low-frequency deep brain stimulation of the nucleus basalis of Meynert can be safely conducted in patients with Parkinson's disease dementia

DBS Safe But Not Beneficial in Parkinson’s Dementia

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No consistent improvements seen in primary cognitive outcomes, resting state functional MRI
Patterns of cortical β-amyloid and tau are not different for patients with Parkinson's disease who are cognitively normal or with mild cognitive impairment and for healthy adults

Cognitive Status Doesn’t Impact Cortical Aβ, Tau in Parkinson’s

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Cortical Aβ, tau does not differ in Parkinson's patients who are cognitively normal, with MCI
For patients with Parkinson's disease

High-Intensity Treadmill Exercise Feasible in Parkinson’s Disease

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Mean change in Unified Parkinson's Disease Rating Scale motor score lower for high-intensity exercise
Parkinson's disease patients with depression have impaired white matter integrity

Impaired White Matter Integrity for Depression in Parkinson’s

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Reduced fractional anisotropy values in left anterior corona radiata, left cingulum of depressed patients
For patients with Parkinson's disease

More Men Than Women With Parkinson’s Have Caregivers

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Caregivers of men report greater strain; women have faster rate to using a paid caregiver than men
The presence of multiple LRRK2 risk variants is associated with a younger age at onset of Parkinson's disease

LRRK2 Variants Linked to Lower Age at Onset of Parkinson’s

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Participants with three risk variants of LRRK2 have significantly lower age at onset than noncarriers