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Patients with prior histories of drug abuse

Researchers ID Patients More Prone to Long-Term Opioid Use

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People with a history of smoking or abusing drugs at highest risk of long-term use
Many HIV-infected patients have chronic pain

HIV-Infected Patients Frequently Have Chronic Pain

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Patients with moderate-severe chronic pain more likely to take antidepressants, prescription opioids
Adverse health behaviors in adolescence are only moderately associated with later musculoskeletal pain in adulthood

Adolescent Lifestyle Not Strongly Tied to Later Muscular Pain

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Smoking, alcohol use, overweight/obesity weakly tied to later pain
An α-melanocyte-stimulating hormone analog

Afamelanotide Beneficial in Erythropoietic Protoporphyria

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Improvement in number of hours of direct exposure to sunlight without pain, quality of life
Prescription Drug Monitoring Programs

Prescription Drug Monitoring Programs Offer Multiple Benefits

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Info in PDMP used to change clinical decisions, guide opioid prescribing, facilitate communication
A new naloxone sustained release capsule appears to be safe and efficacious for opioid-induced constipation

New Naloxone Capsule Safe for Opioid-Induced Constipation

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Sustained release formula efficacious, with no indication of opioid withdrawal or increase in pain
Physicians who are ill-informed about opioids may be unintentionally contributing to their misuse

Many Primary Care Physicians Misinformed About Opioids

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Nearly half questioned were misinformed about potential for abuse
For patients with chronic pain

Methadone Linked to Initial QTc Prolongation in Chronic Pain

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Nonsignificant increase in QTc in first month after initiating methadone, which does not persist
Medical marijuana may be useful in treating chronic pain and spasticity

Moderate-Quality Evidence for Marijuana Rx for Pain, Spasticity

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Review of 79 studies indicates only low-quality evidence for other conditions
Pain is prevalent in more than half of patients with multiple sclerosis

Anxiety Independently Predicts Pain in Patients With MS

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Research confirms high prevalence of pain, affecting more than half of those with multiple sclerosis