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Opioids that have features that make them hard to abuse may be linked to a drop in both the number of prescriptions and overdoses of these drugs

Changing Opioid Rx Formulations May Help Curb Abuse

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As opioid market changed, number of prescriptions, overdoses dropped, but heroin overdoses went up
Both residents and attending physicians are only partly compliant with national opioid prescribing and monitoring guidelines

Attending Physicians, Residents Similar in Opioid Rx Monitoring

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Residents provide more early refills; also see more patients at higher misuse risk
For patients with knee osteoarthritis

Meta-Analysis: Valgus Knee Bracing Helps Pain in Knee OA

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Small, statistically significant effect for pain compared with group that used control orthosis
Acetaminophen may do more than simply dull pain -- it may also dull positive and negative emotions

Acetaminophen Appears to Blunt Emotional Response

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Research involved two experiments, each enlisting about 80 college students
Aerobic exercise may help reduce perceived pain interference resulting from diabetic peripheral neuropathy

Exercise Cuts Pain Interference From Diabetic Neuropathy

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Aerobic exercise intervention doesn't appear to change pain severity measures
A mindfulness program appears to be beneficial for patients with chronic pain

Mindfulness Program Beneficial for Chronic Pain

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Significant effect on primary outcome measure of the Short Form-36 vitality scale
Almost half of colorectal cancer survivors with pain interference (PI) during the initial phase of care have continued PI post-treatment

Half of Colorectal Cancer Survivors Have Continued Pain

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Cardiovascular and pulmonary comorbidities tied to continued pain
Botulinum toxin-A appears to be beneficial for painful diabetic neuropathy

Botulinum Toxin-A Beneficial in Painful Diabetic Neuropathy

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Meta-analysis of two studies shows clinically significant improvement of 'minimum change in pain'
Acetaminophen does not appear to help ease lower back pain and offers little relief for the most common form of arthritis

Acetaminophen Appears Lacking in Low Back Pain

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And only a small, not clinically important benefit in osteoarthritis of hip/knee
Almost a quarter of opioids that are prescribed for chronic pain are misused

Misuse of Prescribed Opioids in One-Quarter

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And about 10 percent of patients with prescriptions become addicted