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In 2015

Serious Suffering Affects Almost Half of Those Who Die Yearly

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Vast majority who experience serious health-related suffering have no palliative care, pain relief
For patients with discogenic low back pain

Intradiscal Electrothermal Therapy Cost-Effective

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Findings based on comparison to femoral ring allograft for discogenic low back pain
For patients with noncancer pain and opioid-induced constipation

Naloxegol Has No Effect on Opioid Dose in Opioid-Tied Constipation

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Centrally-mediated analgesia was maintained during treatment with naloxegol in noncancer pain, OIC
Vitamin D deficiency may be associated with increased neuropathic pain in patients with rheumatoid arthritis

Vitamin D Deficiency Tied to Neuropathic Pain

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Findings among patients diagnosed with rheumatoid arthritis
A 10-mL 1 percent lidocaine paracervical nerve block reduces pain during intrauterine device insertion

Lidocaine Nerve Block Reduces Pain During IUD Insertion

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Pain score lower among patients who receive lidocaine than those who receive placebo
Electrotherapy and acupuncture seem to be beneficial for pain management after total knee arthroplasty

Electrotherapy, Acupuncture Ease Post Knee Arthroplasty Pain

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Meta-analysis shows drop in use of opioids for electrotherapy; delayed opioid use with acupuncture
Cannabis may alleviate neuropathic pain

Review: Cannabis May Alleviate Neuropathic Pain

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Second review shows no benefit for plant-based cannabis preparation versus nonuse for PTSD
Sensory over-responsiveness in otherwise healthy subjects is associated with a pro-nociceptive state

Higher Pain Expression Tied to Pro-Nociceptive State

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With sensory over-responsiveness, daily non-painful stimuli felt more intensely
Substantially higher opioid prescribing rates persist among cancer survivors

Opioid Prescription Rates Higher in Cancer Survivors

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Higher prescribing rates persist even years after cancer diagnosis

Are Clinicians Overprescribing Gabapentinoids for Pain?

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Non-trivial side effects, no robust evidence for off-label use of gabapentinoids for other types of pain