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Tag: Osteoporosis

In an Endocrine Society guideline update

Romosozumab Added to Guideline for Management of Osteoporosis

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Drug recommended for postmenopausal women at very high fracture risk but not at high risk for heart disease, stroke
Supplementation with vitamin D alone does not appear to reduce the risk for fracture

Vitamin D Supplementation Alone May Not Reduce Fracture Risk

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However, meta-analysis shows significant reduction in any, hip fracture with vitamin D plus calcium
Patients with atopic eczema have an increased risk for fracture

Fracture Risk Increased in Adults With Atopic Eczema

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Fracture risk up with increasing eczema severity, with strongest associations for spinal, pelvic, hip fracture
Short sleep duration is associated with lower bone mineral density and a higher risk for osteoporosis among postmenopausal women

Less Sleep Tied to Lower Bone Mineral Density in Women

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Higher risk for osteoporosis also seen with less than five hours of sleep per night
There is a dose-dependent relationship between diagnosis of osteoporosis and statin treatment

Statins Tied to Osteoporosis in Dose-Dependent Manner

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Low-dose statins may offer protective effect against osteoporosis
Medicare could save billions of dollars if secondary fractures could be prevented with improved osteoporosis screening

Medicare Spends More Than $6 Billion on Secondary Fractures

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A fracture should trigger clinical attention to reduce the risk for future fractures, authors say
A new measure derived from conventional X-rays and a machine learning algorithm is effective for assessing bone-specific effects of osteoporosis treatment

Tool Uses Spine X-Rays to Assess Response to Osteoporosis Tx

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Bone structure value determined by software tool significantly correlated with bone mineral density
Osteoporosis is common in patients undergoing total joint arthroplasty

Osteoporosis Undertreated in Joint Replacement Patients

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Nearly 25 percent of patients meet treatment criteria, but only 5 percent get prescription
Cerebral palsy is associated with an increased risk for osteoporosis and osteoarthritis

Adults With Cerebral Palsy at Higher Risk for Osteoporosis

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U.K. study also shows association between CP and osteoarthritis when adjusting for other factors
For postmenopausal women with osteoporosis

Romosozumab Increases Bone Formation, Cuts Bone Resorption

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Lower values for resorption end points at month two persisted to month 12, indicating reduced turnover