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Tag: Organ Transplants

Kidney transplantation among elderly people with end-stage renal disease can be successful

Kidney Transplants From, to Extreme Elderly Feasible in ESRD

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Benefit seen for extremely elderly receiving kidney transplants from similarly aged deceased donors
Transplanting hepatitis C virus-infected kidneys into uninfected recipients and then treating patients with antiviral therapy leads to a higher quality of life and is less costly than waiting for transplantation with an uninfected kidney

Model Shows Hep C-Infected Kidney Transplants Beneficial, Cost-Effective

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Transplant plus antiviral therapy improves quality of life, reduces health care costs for recipients
The distance from a patient residence to transplant center seems not to impact transplant referral and evaluation initiation among those with end-stage kidney disease

Distance to Kidney Transplant Center Does Not Affect Referral

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No impact found on transplant referral and evaluation initiation based on distance for ESKD patients
The composition of CD8+ T cells one year after kidney transplantation is associated with the risk for subsequent transplant failure

CD8+ T Cell Composition Tied to Risk for Kidney Transplant Failure

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CD8+ T cell composition at one year after transplant may identify those at higher risk for graft failure
There has been an increase in survival after pediatric kidney transplantation since 1970

Survival After Pediatric Kidney Transplant Drastically Improved

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Survival up from 1970-1985 to 2005-2015 mainly due to drop in deaths from CV causes, infections
Virtual cross-matching may reduce cold ischemia time for donor organs in kidney transplants

Virtual Cross-Matching May Speed Kidney Transplant Process

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Cold ischemia time for donor kidneys reduced after implementation of virtual cross-matching program
For patients undergoing living kidney transplants

Promoting Mixed Chimerism Promising in Kidney Transplants

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Complete or partial immunosuppressive drug withdrawal without rejection achieved in some
A nationalized kidney paired donation program results in equivalent outcomes compared with control living kidney donor transplant

Outcomes Positive With National Kidney Paired Donation Program

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Graft failure, mortality no different for National Kidney Registry, control living donor transplant recipients
Structural features of kidneys from living donors may predict death-censored graft failure in recipients

Structural Traits of Living Donor Kidneys May Predict Graft Failure

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Interstitial fibrosis/tubular atrophy, larger cortical nephron size, smaller medullary volume predict failure
Considerable differences in histologic categorization are seen in sequential biopsies in deceased donor kidneys that undergo multiple procurement biopsies prior to transplantation

First-Biopsy Results for Deceased Donor Kidneys Questioned

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No association seen between first-biopsy findings and posttransplant outcomes for deceased donor kidneys