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County-level economic and other social conditions explain the geographic disparities in overdose rates across the country

Geographic, Social Variances Tied to Higher Drug-Related Mortality

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Economic, social conditions, and family distress tied to higher drug mortality rates
Adolescents with pre-existing mental health conditions and treatments are more likely to receive any opioid and to transition to long-term opioid therapy

Opioid Receipt Up for Teens With Mental Health Conditions

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Teens with pre-existing mental health conditions, tx more likely to transition to long-term opioid use
The odds of opioid prescription are increased for patients with head and neck cancer versus those with lung or colon cancer

Odds of Opioid Prescriptions Up in Head and Neck Cancer Patients

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More oxycodone tablets provided per prescription for HNCA versus lung and colon cancer
Opioid-involved overdoses are continuing to increase

CDC: Opioid-Involved Overdoses Up July 2016 to Sept. 2017

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Average increase of 5.6 percent/quarter in rate of ER visits with suspected opioid-involved overdoses
Opioid treatment is not superior to non-opioid treatment for improving pain-related function over 12 months

Opioids Don’t Top Non-Opioids for Pain-Related Function

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Findings in patients with moderate-to-severe chronic back pain, hip or knee osteoarthritis pain
Nationally

Pediatric Opioid-Related Hospital, ICU Admissions on the Rise

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Rate of pediatric hospitalization, ICU admission increased, 2004 to 2015
Introduction of a new model of screening and protocoled treatment with medications for opioid addiction treatment

Treatment Model Linked to Drop in Post-Incarceration Overdoses

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Introduction of model to treat opioid use disorder tied to drop in overdose deaths after incarceration
Many patients with non-cancer-related chronic pain prescribed long-term opioids may wish to taper their opioid use

Chronic Opioid Users May Wish to Taper Opioid Use

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In study completers, median morphine equivalent daily dose fell from 288 mg to 150 mg in four months
Intravenous acetaminophen with or without ketorolac is associated with reduced opioid consumption and cost of care after scoliosis surgery in adolescents

Opioids Plus Acetaminophen, Ketorolac Cost-Effective Post-Sx

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In children having scoliosis surgery, combo is linked to reduced opioid intake compared with opioids alone
Antidepressant medication adherence is associated with cessation of long-term prescription opioid use among patients with non-cancer pain

Treating Depression Found to Up Successful Opioid Cessation

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Taking antidepressants helped non-cancer pain patients successfully stop long-term opioid use