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Use of medications for opioid use disorder is associated with a reduction in all-cause and opioid-related mortality after opioid overdose

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

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Minority of opioid overdose survivors receive MOUD; buprenorphine, MMT linked to reduced mortality
The U.S. Drug Enforcement Administration's 2014 ruling to reschedule hydrocodone combination products coincided with an increase in illicit trading of opioids through online illicit markets (cryptomarkets)

Illicit Opioid Trade Up With Restrictions on Hydrocodone

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2014 ruling to reschedule hydrocodone combo products coincided with rise in cryptomarket trade
Risk factors for opioid overdose among hospitalized patients include being age 65 years or older

Older Age, ICU, Poor Renal Fcn Up Risk of Opioid OD in Hospital

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For hospitalized patients, risk also increased for those receiving three or more CNS antidepressants
Stigmatizing attitudes toward those who use opioids are associated with lower support for two evidence-based opioid harm reduction strategies

Public Support Only Moderate for Opioid Harm Reduction Strategies

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Stigmatizing attitudes toward opioids linked to lower support for two evidence-based strategies
Nine online networks

FDA Warns Websites Marketing Unapproved Opioids

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As part of comprehensive effort to target online sales, networks operating 53 sites received warnings
Higher daily average inpatient pain scores and higher postoperative opioid consumption are associated with a subsequent persistent opioid use of up to six months among pediatric patients undergoing major oncologic surgery

Factors ID’d for Persistent Opioid Use After Pediatric Surgery

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Findings in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemo
From 2001 to 2016 there was an increase in the number and percentage of opioid-related deaths; in addition

Studies ID Impact of U.S. Opioid-Related Mortality, Rx Patterns

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Burden of deaths up; most patients receiving opioid analgesics use immediate-release formulations
The widespread shortages of injectable opioids and small-volume parenteral solutions are jeopardizing patient care and placing a strain on hospital operations

ASHP: SVP, Injectable Opioid Shortages Threaten Patient Care

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98.4 percent of respondents report moderate, severe shortages of morphine, hydromorphone, fentanyl
The widespread shortages of injectable opioids and small-volume parenteral solutions are jeopardizing patient care and placing a strain on hospital operations

ASHP: SVP, Injectable Opioid Shortages Threaten Patient Care

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98.4 percent of respondents report moderate, severe shortages of morphine, hydromorphone, fentanyl
Patterns of potential opioid misuse are positively associated with subsequent opioid overdose

Patterns of Potential Misuse Help Assess Risk of Opioid Overdose

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Positive link for subsequent opioid overdose with greater numbers of prescribers and pharmacies