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Concurrent use of benzodiazepine receptor modulators and opioids and of nonselective and selective benzodiazepine receptor modulators increased from 1999-2000 to 2013-2014

Benzodiazepine, Opioid Co-Usage Up in the United States

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Increases also noted in co-use of nonselective and selective benzodiazepine receptor modulators
The percentage of individuals prescribed an opioid is higher in rural than urban areas

CDC: Opioid Prescribing Higher in Rural Versus Urban Areas

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Odds of receiving an opioid prescription dropped significantly after March 2016 in all county groups
Over time

CDC: Slight Hike in Prevalence of Gastroschisis Since 2006-2010

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Prevalence higher in areas with high and medium versus low opioid prescription rates
Mandated neonatal abstinence syndrome surveillance and reporting allows state health departments to quantify incidence and informs programs and services

Mandated Neonatal Abstinence Reporting Helps Quantify Cases

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Five of six states with mandatory reporting receive case reports within 30 days of diagnosis
From 2007 to 2016

Medication Treatment for Substance Abuse Up in Facilities

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2007 to 2016 saw increase in use of medication treatment, reaching 36.1 percent in 2016
For the first time in history

Opioids Now More Deadly for Americans Than Traffic Accidents

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Preventable injuries are the third leading cause of death in the United States
Persistent opioid use at three and six months remains high among patients undergoing treatment for head and neck squamous cell cancer

Persistent Opioid Use High in Head, Neck Cancer Patients

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Opioid use before treatment, tobacco use are risk factors for ongoing opioid use
From 1999 to 2017

Drug Overdose Death Rate Increasing Among Middle-Aged Women

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1999 to 2017 saw increases in deaths involving antidepressants, cocaine, heroin, synthetic opioids
Prescribed opioids are associated with an increased risk for community-acquired pneumonia requiring hospitalization among persons with and without HIV

Rx Opioids Up Pneumonia Risk in Patients With, Without HIV

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Risk greatest with higher-dose opioids and opioids with immunosuppressive properties
A rule with six criteria can determine whether patients can be safely discharged from the emergency department after a one-hour observation period following prehospital naloxone administration

Discharge One Hour After Naloxone for OD May Be Option

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New rule has sensitivity, specificity of 84.1, 62.1 percent for patients receiving prehospital naloxone