Tag: Opioids
Study Looks at Co-Use of CYP2D6-Metabolizing Opioids, Antidepressants in Seniors
CYP2D6-inhibiting antidepressants linked to worse outcomes than CYP2D6-neutral antidepressants when used with CYP2D6-metabolizing opioids
Low Quantity of Opioids Used After ED Discharge for Acute Pain
63 percent of opioid tablets prescribed unused in the two weeks after discharge; use varied across pain conditions
Small Number of Procedures Account for Large Number of Opioid Prescriptions
Cesarean delivery accounts for highest proportion of MMEs dispensed after surgery among individuals aged 18 to 44 years
Supreme Court Rejects Purdue Pharma Opioid Settlement
Pediatric Surgical Opioid Prescribing Concentrated Among a Few Procedures
Tonsillectomy/adenoidectomy accounted for most MMEs in opioid prescriptions dispensed after surgery
Multimodal Intervention Does Not Cut Opioid Overdose Deaths
No significant reduction seen in opioid overdose deaths with implementation of evidence-based practice strategies
Prenatal Opioid Exposure Not Tied to Neuropsychiatric Disorders in Offspring
Prenatal opioid exposure not linked to a clinically meaningful increase in risk for neuropsychiatric disorders
Pediatric Prescription-Opioid Overdose Visits to ED Increased in 2020
Uptick follows a decrease from 2008 to 2019 and may be pandemic-related, the authors say
Elimination of Extended-Release Opioids Can Improve Outcomes After TKR
Reduction seen in antiemetic use, nonsignificant reduction in length of stay, increase in proportion discharged to home
Prescription Opioids Linked to Increased Risk for Serious Fall Events
Findings seen among adults of all ages, especially those aged 85 years or older; risk highest in first 28 days after initiation
