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Fewer than half of California pharmacies provide correct information about disposal of antibiotics and opioids

Few Pharmacies Provide Correct Info on Medication Disposal

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Only 11 percent of California pharmacies reported on-site take-back programs for antibiotic, opioid disposal
The severity of pediatric admissions for acute opioid ingestions

Number of Children With Opioid Poisonings Increasing

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Percentage of critical care admissions and suicidal intent increased in each era
Automotive assembly plant closures from 1999 to 2016 were associated with increases in opioid overdose mortality

Closures of Automotive Assembly Plants Tied to Opioid OD Deaths

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Increases in opioid overdose mortality largest for non-Hispanic white men aged 18 to 34, 35 to 65 years
Older teens may have similar risk factors for prescription opioid overdose as adults

Prescribing Practices Can Mitigate Opioid Overdose Risk for Teens

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Lowest amount of opioids, short-acting opioids, avoiding concurrent use of opioids and benzodiazepines cut risk
Buprenorphine treatment may be needed for several years after an opioid overdose to reduce the risk of overdose and other adverse events

Overdose, Relapse After Buprenorphine Discontinuation High

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The longer patients continue with buprenorphine treatment, the lower their risk of adverse outcomes
New warnings about the risk for dangerous breathing difficulties when gabapentinoids are used with opioids or by certain patients must now appear on product labels

Gabapentinoids, Opioids Combo Carries Risk for Breathing Problems

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Serious breathing problems can occur in patients who use gabapentinoids with opioids or other CNS depressants
The rate of opioid-related suicides as well as unintentional deaths significantly increased from 2000 to 2017

Opioid-Related Suicides Down, Rate of Unintentional Deaths Up

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Crises of opioid overdose deaths and suicide do not appear closely linked
Coprescription of benzodiazepines and opioid agonist treatment is associated with an increased risk for drug-related poisoning mortality in opioid-dependent individuals

Benzodiazepines With Opioid Agonist Tx May Up Mortality Risk

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Coprescription of z-drugs with OAT also linked to increased risk for drug-related poisoning mortality
The rate of in-hospital births with neonatal abstinence syndrome was 6.7 per 1

Rates of Neonatal Abstinence Syndrome Remain High in U.S.

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Highest rates of neonatal abstinence syndrome seen in lowest income quartile, rural areas, Northeast
Among cancer survivors

Factors Predict Adverse Opioid-Related Outcomes in Cancer Survivors

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Demographic, cancer, and treatment factors can predict outcomes with high level of discrimination