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Obesity enhances local myofibroblast content and stiffness-promoting extracellular matrix components in mammary adipose tissue

Obesity May Fuel Breast CA Via Change in Breast Tissue Structure

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Findings suggest obesity can trigger structural changes in extracellular matrix
A single nucleotide variant in the FTO obesity locus disrupts a conserved motif

Role of SNP Variant in FTO Explored in Obesity

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Study identifies mechanistic basis for the strongest genetic association with obesity
Exercise training combined with phototherapy is associated with improvements in the metabolic profiles of obese women

For Obese Women, Exercise Plus Phototherapy Beneficial

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Reduction in fat mass, delta of percentage change in fat mass, HOMA-IR index
For obese individuals

Home-Based Device Beneficial for Obese Patients With Knee OA

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Biomechanical device tied to improvement in all gait parameters at three, 12 months
The ReShape Integrated Dual Balloon System has been approved by the U.S. Food and Drug Administration to combat adult obesity. Inflated inside the stomach

FDA Approves Balloon Device to Treat Obesity

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Inflated in stomach, it may create sense of fullness
Weight loss is considered a major health goal for people who are obese

Most Obese Patients Never Reach a Healthy Weight

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Though odds of losing 5 percent of body weight were better, three-quarters gained it back in five years
One-third of young adults in the United States are too overweight to be in the military

Weight Disqualifies 1 in 3 Young Adults From U.S. Military

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61 percent rise in obesity among the U.S. military's active duty forces since 2002
For overweight adults with diabetes mellitus

Lifestyle Intervention Can Ward Off Obesity-Related Knee Pain

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Findings show benefit at one year for overweight adults with diabetes mellitus at high risk of knee pain
Weight loss is a strong predictor of mortality in patients with rheumatoid arthritis

Weight Loss Predicts Mortality in Rheumatoid Arthritis

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Highest risk seen with high annual weight loss rate, low BMI in previously obese
Use of metformin during pregnancy doesn't impact the birth weight of infants born to obese mothers

Metformin in Pregnancy Shows No Effect on Infant Birth Weight

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However, metformin can help to control women's blood glucose, researchers find