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Tag: Obesity

Benzyl butyl phthalate regulates the mesenchymal stem cell toward adipogenesis by inducing epigenetic stress

Plastics Chemical BBP Exposure May ‘Program’ Obesity

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BBP exposure enhances lipid accumulation and adipogenesis in dose-dependent manner
Pedestrian-friendly ("walkable") neighborhoods have reduced rates of diabetes

City Planning for Walkability May Help Curb Diabetes Rates

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The higher the walkability, the lower the rates of diabetes
Obese adolescents may have lower levels of the hormone spexin than normal-weight adolescents

Low Levels of Hormone Associated With Teen Obesity

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Teens with the lowest levels of spexin more than five times as likely to be obese
AMPK activation by metformin is associated with inhibition of interstitial fibrosis and suppression of transforming growth factor β-1

Metformin Combats Adipose Tissue Expansion Via AMPK

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AMPK activation is linked to inhibition of interstitial fibrosis, suppression of TGF-β1
A lifestyle intervention preceding infertility treatment does not result in higher rates of vaginal birth among obese infertile women

Lifestyle Intervention Before Infertility Treatment No Benefit

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Lifestyle intervention preceding infertility treatment doesn't up vaginal birth rates in obese women
Self-measured waist circumference has a clinically important false-negative rate compared with professionally-measured waist circumference

Self-Measured Waist Circumference Often Falls Short

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Clinically important false-negative rate for self-measured waist circumference
besity and Roux-en-Y gastric bypass (RYGB) affect the skeletal muscle proteome

Obesity, RYGB Impact Skeletal Muscle Proteome

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Array of changes in protein abundance in skeletal muscle before and after RYGB surgery
For overweight and obese subjects

Trans-Resveratrol, Hesperetin Up Glo1 Expression, Metabolic Health

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tRES-HESP coformulation linked to improvements in metabolic and vascular health
Neuronal growth hormone secretagogue receptor is involved in regulating energy metabolism

Neuronal GHS-R Involved in Regulating Energy Metabolism

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Deletion of neuronal Ghsr in mice almost completely prevents diet-induced obesity
The body mass index linked to the lowest rate of all-cause early mortality is rising

Excess Weight May Not Equal Early Mortality After All

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BMI linked to lowest rate of all-cause early death up by more than three units since 1970s