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Tag: Muscle Problems

ZRT- and IRT-like protein 14 upregulation in skeletal muscles may play a role in cancer-related muscle loss

Excess Zinc in Muscles May Drive Cancer-Related Wasting

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ZIP14 may be a therapeutic target for its treatment
In a case report published online June 18 in BMJ Case Reports

Tattoo-Linked Complications ID’d in Immunosuppressed Female

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Inflammatory myopathy identified in woman with cystic fibrosis on long-term immunosuppressants
For infants with type 1 spinal muscular atrophy who have two copies of the survival motor neuron (SMN) 2 gene

AAN: New Drug May Help Infants With Spinal Muscular Atrophy

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RG7916 increases survival motor neuron protein level, with 6.5-fold increase noted with highest dose
For infants with type 1 spinal muscular atrophy who have two copies of the survival motor neuron (SMN) 2 gene

AAN: New Drug May Help Infants With Spinal Muscular Atrophy

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RG7916 increases survival motor neuron protein level, with 6.5-fold increase noted with highest dose
Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle

Young Adults With T1DM Show Muscle Metabolic Deficiencies

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Lower mitochondrial oxidative capacity in skeletal muscle of physically active young adults with T1DM
Nusinersen is associated with significant and clinically meaningful improvement in motor function among children with later-onset spinal muscular atrophy

Nusinersen Beneficial in Later-Onset Spinal Muscular Atrophy

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Significant improvement in motor function compared with sham procedure among children with SMA
The prevalence of work-related musculoskeletal disorders appears to be high for at-risk physicians

Higher Risk of Musculoskeletal Disorders in Some Physicians

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Increasing risk for work-related musculoskeletal disorders, particularly in procedural specialists
New classification criteria have been developed for idiopathic inflammatory myopathies

Criteria Developed for Idiopathic Inflammatory Myopathies

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Classification criteria developed from rheumatology, dermatology, neurology, pediatric clinic data
Gene replacement therapy is beneficial in spinal muscular atrophy type 1

Gene Replacement Tx Beneficial in Spinal Muscular Atrophy

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And nusinersen improves motor-milestone response for infants with spinal muscular atrophy
Higher levels of echo intensity on ultrasound are associated with lower levels of muscle strength and greater frailty in the elderly

Ultrasound Echo Intensity Is Potential Frailty Biomarker

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High levels of echo intensity associated with lower muscle strength in the elderly