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Tag: Muscle Problems

Skeletal muscle mass is inversely associated with the incidence of cardiovascular disease among middle-aged and older adults

Higher Skeletal Muscle Mass May Lower Long-Term Risk for CVD

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Compared with the lowest tertile, those in highest SMM tertile had 81 percent lower risk for CVD event
Enterovirus-specific antibodies have been identified in the cerebrospinal fluid of pediatric cases of acute flaccid myelitis versus controls

Antiviral Antibodies ID’d in CSF of Acute Flaccid Myelitis Cases

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High levels of CSF enterovirus-specific antibodies identified in AFM cases versus controls
Surveillance data for acute flaccid myelitis suggests a viral etiology

Data Suggest Viral Etiology for Pediatric Acute Flaccid Myelitis

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Seventy-nine percent of confirmed cases of AFM had antecedent respiratory or febrile illness
Initiating donepezil to manage symptoms of Alzheimer disease or other dementias is associated with a higher risk for 30-day admission to the hospital with rhabdomyolysis compared with initiating rivastigmine or galantamine

Donepezil Ups Risk for Hospital Admission for Rhabdomyolysis

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Donepezil linked to increased risk for admission with rhabdomyolysis versus rivastigmine, galantamine
Hormone therapy does not significantly impact muscle mass in postmenopausal women

Hormone Tx Not Tied to Change in Muscle Mass in Older Women

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No significant beneficial or detrimental association seen in postmenopausal women
Low muscle mass is associated with all-cause and cardiovascular mortality risk in the elderly

Low Muscle Mass in the Arms, Legs Tied to Mortality in Elderly

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Muscle mass more predictive of mortality than visceral fat, total fat in older women
A tool has been developed that can improve standardization and transparency when describing cell therapies

Experts Develop Standardized Tool for Describing Cell Therapies

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Consensus reached on contents of DOSES tool for improving standardization and transparency
For patients with type 2 diabetes

Poor Glycemic Control Linked to Sarcopenia in T2DM

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Correlation independent of major covariates including anthropometric factors and diabetes duration
The burden of musculoskeletal diseases increased significantly worldwide between 2000 and 2015

Global Burden of Musculoskeletal Diseases on the Rise

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Significant increases seen worldwide, but burden highest in Europe
Limited evidence suggests that nusinersen treatment provides long-term benefits for children with later-onset spinal muscular atrophy

Nusinersen Promising for Later-Onset Spinal Muscular Atrophy

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Phase 1/2 studies reveal long-term improvement in motor function for children with SMA type II and III