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Tag: Multiple Sclerosis

First Biosimilar Approved to Treat Multiple Sclerosis

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Tyruko, biosimilar to Tysabri (natalizumab) injection, approved for treatment of clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease

Patients Say Ketogenic Diet Aids Multiple Sclerosis Symptoms

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Even after ketogenic diet trial ended, most patients maintained a diet shift toward fewer carbohydrates and added sugar

Fatigue Correlates With Disability in Patients With Relapsing-Remitting MS

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Lower disability, better physical condition, higher daily-living activity predict lower fatigue

2001 to 2020 Saw Shift in Rx for Disease-Modifying Therapy for Multiple Sclerosis

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Oral disease-modifying therapies dominated new initiations by 2020 to 62.3 percent

Early Treatment of Demyelination Events Cuts Long-Term Disability in MS

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Reduced risk for reaching EDSS 3.0, secondary progressive MS, sustained disease progression seen with very early treatment

Genes Identified in Association With Multiple Sclerosis Severity

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Significant association identified with rs10191329 in the DYSF-ZNF638 locus, with risk allele shortening time to needing walking aid

Pro-Inflammatory Diet Linked to Worsening Relapse Rate in MS

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Association seen between energy adjusted dietary inflammatory index score and fluid-attenuated inversion recovery lesion volume

Rituximab Not Noninferior to Ocrelizumab for Relapsing-Remitting MS

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Cumulative hazard of relapses higher among patients treated with rituximab versus ocrelizumab

Whites Have Highest Prevalence of Multiple Sclerosis in the United States

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Highest prevalence seen in those aged 45 to 64 years; prevalence also increased with each degree of latitude

AAN: Teriflunomide Reduces Clinical Events in Radiologically Isolated Syndrome

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Significant reduction seen in clinical events with teriflunomide; nonsignificant reduction noted in Gd+ lesions, new or enlarging T2 lesions