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Tag: Multiple Sclerosis

Exposure to a surgical procedure requiring anesthesia does not seem to increase the risk for postoperative multiple sclerosis relapse

MS Relapse Risk Not Increased in Postoperative Period

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Odds of postoperative versus preoperative relapse were not increased in unadjusted, adjusted analyses
Obesity seems to be associated with increased odds of pediatric multiple sclerosis

Obesity Linked to Increased Risk for Pediatric Multiple Sclerosis

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Obese patients have significantly more relapses on first-line treatment with IFN beta, glatiramer acetate
For patients with severe progressive multiple sclerosis

Standing Frame Program Can Up Motor Function in Progressive MS

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Motor function increased significantly but not to degree considered a priori as clinically meaningful
Multiple sclerosis (MS) patients have an elevated cancer risk compared with non-MS controls

Increased Cancer Risk Seen in Multiple Sclerosis Patients

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Cancer risk up for MS patients versus non-MS controls, especially in respiratory, urinary, CNS organs
Patients with pediatric-onset multiple sclerosis have a more rapid reduction in information-processing efficiency over time in adulthood

Cognitive Consequences Worse for Pediatric-Onset Multiple Sclerosis

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Patients with POMS have more rapid reduction in information-processing efficiency over time
Simvastatin's beneficial effects on clinical outcomes and brain atrophy in patients with multiple sclerosis are largely independent of cholesterol levels

Model Explores How Statins Alter Multiple Sclerosis Outcomes

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Loss of brain volume reduced in patients taking simvastatin independent of effect on cholesterol level
The International Pediatric Multiple Sclerosis Study Group has updated standards for future clinical trials in pediatric multiple sclerosis; the new recommendations were published in the May 28 issue of Neurology.

Recommendations Developed for Pediatric Multiple Sclerosis Trials

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Biological rationale exists for using treatments proven efficacious in adults with MS for pediatric MS
A new anatomic threshold may be useful for identifying unilateral optic nerve lesions in patients with multiple sclerosis

Thresholds Found for Unilateral Optic Nerve Lesions in MS

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Intereye differences for retinal nerve fiber layer and macular ganglion cell + inner plexiform layer useful
The selective Bruton's tyrosine kinase inhibitor evobrutinib at a dose of 75 mg once daily is associated with fewer enhancing lesions during weeks 12 through 24 among patients with relapsing multiple sclerosis

AAN: Oral BTK Inhibitor Superior to Placebo in Multiple Sclerosis

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Fewer enhancing lesions seen in weeks 12 to 24 for 75 mg evobrutinib once daily versus placebo
Nearly one in five patients referred to a multiple sclerosis specialty center are misdiagnosed

Significant Number of Referred Patients Misdiagnosed With MS

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At MS referral centers, almost one in five new patients have been incorrectly diagnosed with the disease