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Tag: Multiple Myeloma

Xpovio (selinexor) tablets have been approved for use in combination with dexamethasone to treat adults with relapsed refractory multiple myeloma

Xpovio With Dexamethasone Approved for Refractory Multiple Myeloma

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Drug combination approved to treat patients who have failed at least five other treatments
For patients with relapsed multiple myeloma

Cardiovascular AEs Common With Carfilzomib in Multiple Myeloma

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Patients with relapsed multiple myeloma experiencing CVAEs had inferior survival
In a review published in the June 1 issue of The Lancet Oncology

Recommendations Issued for Imaging Use in Multiple Myeloma

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Low-dose whole-body CT recommended over conventional skeletal survey for detection of bone disease
For older patients with blood cancers

Gait Speed Is Prognostic in Older Patients With Blood Cancer

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Decrease in gait speed linked to higher mortality, increased odds of unplanned hospitalization, ED use
For patients with newly diagnosed multiple myeloma

Daratumumab Cuts Risk for Progression in Multiple Myeloma

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Adding daratumumab to lenalidomide + dexamethasone beneficial for newly diagnosed multiple myeloma
A safety statement was issued yesterday by the U.S. Food and Drug Administration regarding risks found to be associated with the investigational use of Venclexta (venetoclax) for treatment of patients with multiple myeloma.

FDA: Higher Risk for Death Found With Venclexta in Multiple Myeloma

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Enrollment suspended for trials investigating Venclexta for treatment of multiple myeloma
A consensus statement for the use of hematopoietic stem cell transplantation in the treatment of multiple myeloma has been developed by Mayo Clinic physicians; the recommendations were published in the March issue of Bone Marrow Transplantation.

Recommendations Issued for HSCT in Multiple Myeloma

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Autologous stem cell transplant remains essential component of MM therapy in eligible patients
For patients with multiple myeloma who are ineligible for stem cell transplantation

Model Predicts Survival in Transplant-Ineligible Myeloma Patients

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U.K. Myeloma Research Alliance Risk Profile predicts overall survival based on data from two trials
For patients with multiple myeloma

HRQoL Scores Decrease With Treatment Line in Multiple Myeloma

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Relatively high scores seen for patients with multiple myeloma in first treatment-free interval
For patients with multiple myeloma in whom treatment with lenalidomide and a proteasome inhibitor has failed

Addition of Elotuzumab Ups PFS in Refractory Multiple Myeloma

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In phase 2 trial, longer progression-free survival for elotuzumab with pomalidomide and dexamethasone