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Tag: Multiple Myeloma

Patients with multiple myeloma may receive a survival benefit from being treated at high-volume facilities

Care at High-Volume Facility May Cut Mortality in Multiple Myeloma

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Mortality did not differ for those treated by NCICCC MM specialists, highest-volume community oncologists
For myeloma patients with progressive disease (PD) after induction therapy

Salvage Therapy Does Not Up Survival for Progressive Myeloma

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Deepening of response through salvage therapy not linked to improved progression-free, overall survival
The combination of selinexor and dexamethasone seems effective in treating patients with multiple myeloma that has not responded to standard therapies

Novel Therapy Treats Triple-Class Refractory Multiple Myeloma

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Partial response or better observed in 26 percent of patients receiving oral selinexor-dexamethasone
An Eastern Cooperative Oncology Group performance status of ≥2 is linked to lower treatment satisfaction in patients with relapsed or refractory multiple myeloma

Patient Preferences Explored in Multiple Myeloma Treatment

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All-oral regimen linked to higher satisfaction with treatment convenience in relapsed, refractory MM
For patients with multiple myeloma receiving immunomodulatory drugs

SAVED Score Can Predict Risk for VTE in Multiple Myeloma

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Score outperforms current NCCN guidelines for MM patients receiving immunomodulatory therapy
The economic burden of disease progression is considerable among multiple myeloma patients receiving drug therapy across all lines of therapy

Cost Burden of Disease Progression High in Multiple Myeloma

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For patients receiving drug therapy, economic burden substantial across lines of therapy
First-degree relatives of patients with hematological malignancies have increased relative risks for the same tumor types and some different hematological malignancies

Hematological Malignancy Risk Up for First-Degree Relatives

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Increased familial relative risks for the same tumor type for most hematological malignancies
A new risk prediction score outperforms current guidelines for predicting venous thromboembolism in multiple myeloma

New Score Predicts Risk for VTE in Those With Multiple Myeloma

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New IMPEDE VTE score outperforms International Myeloma Working Group/NCCN guidelines
Individuals with low- or intermediate-risk monoclonal gammopathy of undetermined significance can experience progression to multiple myeloma within five years

MGUS Can Progress to Multiple Myeloma Within Five Years

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Risk factors associated with progression include IgA isotype, 15 g/L or more monoclonal spike
Symptoms of depression are common among patients diagnosed with hematological malignancy

Depression at Time of Diagnosis May Worsen Survival in Blood Cancers

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Risk for death higher even with depression remission versus never experiencing depression