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1999 to 2020 Saw Decrease in Mortality Due to Infective Endocarditis

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Age-adjusted mortality rates decreased in overall population, but increased in those aged 25 to 44 years

Slow-to-Moderate Weight Loss Linked to Lower Mortality in Knee, Hip OA

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Weight loss has dose-response protective effect on incident hypertension, type 2 diabetes, venous thromboembolism

2020 to 2021 Saw Nonsignificant Decline in Perinatal Mortality Rate

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Late fetal mortality rate was essentially unchanged, while early neonatal mortality rate decreased 4 percent

Cardiovascular Benefits Seen With as Few as 2,600 Steps Daily

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Additional mortality benefits were found at a moderate-to-high versus low step cadence

Adverse Events Up With Immune Checkpoint Blockade Added to Periop Cancer Therapy

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Increase seen in incidence of grade 3 to 4 treatment-related adverse events, adverse events leading to treatment discontinuation

2018 to 2021 Saw Increase in Pregnancy-Linked Drug OD Mortality Ratios

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Mortality ratio increased about threefold for pregnant and postpartum women aged 35 to 44 years

Markers of Inflammation Can Predict 180-Day Mortality in Cirrhosis

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20 markers of inflammation correlated with 180-day mortality; no correlations observed with liver-related admissions

CVD Mortality Similar With Diuretic, ACE Inhibitor, or Calcium Channel Blocker

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Those randomly assigned to receive ACE inhibitor had increased risks for stroke mortality, fatal and nonfatal hospitalized stroke versus diuretic group

High Systolic BP Tied to Higher Cardiovascular Mortality in T2DM

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Similarly, very low diastolic BP increases cardiovascular mortality risk with diabetes

Lipid-Lowering Drugs Save Lives, but Use Decreasing

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In 2019 to 2020, 56 percent of patients with high cholesterol were on statins for primary prevention and 85 percent for secondary prevention