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Acute treatment of migraine with ubrogepant leads to significantly greater rates of pain freedom at two hours than placebo

Ubrogepant Superior to Placebo for Migraine Pain Relief

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More participants reported pain freedom at two hours with 50-mg, 25-mg ubrogepant versus placebo
Migraines are a significant risk factor for Alzheimer disease and all-cause dementia

Migraines Linked to Higher Risk for Dementia, Alzheimer Disease

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However, no link seen between migraines and vascular dementia
Facial involvement in primary headaches occurs infrequently

Facial Involvement in Primary Headaches Occurs Infrequently

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Facial pain reported as independent or additional symptom in 291 patients of 2,912 patient data sets
Evidence-based therapies are available for the acute symptomatic treatment of migraine in children and adolescents

Evidence Supports Meds Used for Pain Relief in Pediatric Migraine

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But evidence insufficient to assess impact of many treatments to reduce headache frequency in youth
Higher levels of caffeinated beverage intake may be a trigger for migraine headache on that day among adults with episodic migraines

Excess Caffeine May Be a Trigger for Episodic Migraine Headaches

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Three or more servings of caffeinated beverages associated with higher odds for headache that day
Compared with placebo

Rimegepant Shows Promise for Relief From Migraine Attacks

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Increase seen in percentage of patients free from pain, from their most bothersome symptom at two hours
Pregnant women with migraine and their offspring have increased risks of several adverse pregnancy and neonatal outcomes

Adverse Outcomes Up for Pregnant Women With Migraine

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Increased risk for several neonatal, postnatal outcomes for offspring exposed to maternal migraine
The prevalence of migraine is elevated for young adults with food insecurity

Migraine Prevalence Up for Food-Insecure Young Adults

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Odds of migraine higher for food-insecure versus food-secure in unadjusted, adjusted analyses
Use of a progressive muscle relaxation smartphone app is associated with a reduction in headache days among adults with migraines

Progressive Muscle Relaxation App Tied to Fewer Migraines

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But patients with depression scores were less likely to use either a headache diary or the app
Migraines in pregnant women are associated with an increased risk for pregnancy-associated hypertension disorders as well as an increased risk for a variety of adverse outcomes in the newborn

Migraines in Pregnancy Tied to Worse Outcomes for Mother, Baby

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Poor outcomes seen in pregnancy for women and at birth, neonatal, and postnatal periods for infants