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Smoking Marijuana Ups Toxic Chemical Levels in Blood, Urine

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However, levels of smoke-related chemicals lower compared with those seen with tobacco smoking

Most older adults using cannabis report initiating use after the age of 60 years primarily to treat pain

Cannabis Use Common in Older Adults

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Most indicate using after age 60 years for medical purposes
New cannabinoid use is associated with elevated rates of adverse outcomes among older adults with chronic obstructive pulmonary disease

Cannabinoid Use Tied to Adverse Outcomes With COPD

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In older adults with COPD, cannabinoid use tied to all-cause mortality, hospitalizations
Prenatal cannabis exposure is associated with a greater risk for psychopathology during middle childhood

Prenatal Cannabis Exposure May Raise Risk for Psychopathology

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Findings seen in middle childhood, especially for maternal cannabis use after knowledge of pregnancy
Alcohol use decreased

Alcohol Abstinence Increased Among Young Adults From 2002 to 2018

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However, increase seen in marijuana use, co-use of alcohol and marijuana
For U.S. adults with problem substance use who use nonmedical opioids

For Substance Abusers, Odds of Opioid Use Up With Cannabis Use

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For adults using nonmedical opioids, odds of opioid use are increased on days when cannabis is used
Patients with prior cannabis use may need higher doses of intraoperative inhaled anesthetic and postoperative opioids

ASA: Cannabis Users May Need More Anesthesia During Surgery

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Also, higher subjective pain scores seen postoperatively among cannabis users
Use of medical marijuana is associated with fewer hospitalizations among patients with sickle cell disease

Medical Marijuana Tied to Fewer Admissions in Sickle Cell Disease

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But no change in opioid use observed for those receiving medical marijuana certification
From 2016 to 2018

Cannabis Use Increased Among Older Adults From 2016 to 2018

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Prevalence of use about double for men versus women; increased for almost all age groups
Individuals with depression are at a higher risk for cannabis use

Risk for Cannabis Use Increased Among Adults With Depression

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And odds of past-month cannabis use and depression up from 2005-2006 to 2015-2016 in U.S. adults