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Tag: Macular Degeneration

There was a decrease in the five-year risk for age-related macular degeneration by birth cohorts throughout the 20th century

AMD Risk Has Dropped By Birth Cohort Throughout 20th Century

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Generational association remains significant after adjustment for age, sex, other confounders
Human embryonic stem cell-derived retinal pigment epithelial cells transplanted subretinally are safe for advanced dry-form age-related macular degeneration (AMD) as well as for atrophic AMD and Stargardt disease

AAO: Stem Cell Retinal Pigment Epithelial Cells Safe in Dry AMD

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And subretinal hESC-derived RPE suspension safe in age-related macular degeneration, Stargardt disease
Combination therapy consisting of ranibizumab plus verteporfin photodynamic therapy is superior to ranibizumab monotherapy for treatment of eyes with polypoidal choroidal vasculopathy

Combo Tx Superior for Polypoidal Choroidal Vasculopathy

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Ranibizumab plus verteporfin photodynamic therapy beats monotherapy in best-corrected visual acuity
Dietary supplementation does not lead to measurable increases in macular pigment optical density

Supplements Don’t Measurably Increase Macular Pigment Density

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In offspring of macular degeneration patients, lutein plus zeaxanthin does not lead to density change
Patients with age-related macular degeneration have altered plasma metabolomic profiles compared with those without the condition

Metabolomic Profiles Differ With Macular Degeneration

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The most significant metabolites identified are part of the lipid pathways
An inexpensive over-the-counter antioxidant/zinc supplement -- dubbed the "Age-Related Eye Disease Study" supplement -- may help preserve vision in older people and is also cost-effective

Supplement Deemed Effective, Cost-Saving in Wet AMD

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Patients taking supplements would need fewer anti-VEGF therapies, researchers conclude
There may be a functional interaction between dietary carbohydrates

Functional Interaction Seen for Dietary Carbohydrates With AMD

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Consumption of high-glycemia diet resulted in many features of age-related macular degeneration
Approximately one-fourth of eyes deemed to be normal based on eye examination by primary eye care physicians have age-related macular degeneration determined by fundus photography and trained raters

Undiagnosed Macular Degeneration Appears Common

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Nearly one-fourth of eyes deemed normal in primary care eye exam found to have AMD
For Chinese

Effect of AMD on Vision-Specific Functioning Differs by Ethnicity

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Early and late age-related macular degeneration tied to worse VSF for Chinese, not Indian, Malay adults
Behavioral activation plus low vision rehabilitation with an occupational therapist is more effective than conventional low vision optometry services for patients with age-related macular degeneration

Behavioral Activation Plus Low Vision Rehab Beneficial in AMD

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More effective than conventional optometric low vision services for age-related macular degeneration