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Clinical manifestations of systemic lupus erythematosus vary by racial and ethnic groups

Lupus Manifestations Appear to Differ by Race, Ethnicity

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Increased risk for severe manifestations seen among blacks, Hispanics, and Asians/Pacific Islanders
Mortality from systemic lupus erythematosus is significantly higher among blacks

CDC: Racial Disparity Seen With Lupus-Related Deaths

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Deaths among blacks occur sooner after diagnosis and at younger age compared with whites
Adverse childhood experiences are associated with worse patient-reported systemic lupus erythematosus outcomes

Adverse Childhood Experiences Linked to Worse Lupus Outcomes

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More adverse childhood experiences associated with depression, poor overall health for those with SLE
More than 60 percent of patients with lupus report that the disease has a large effect on their emotional and mental well-being

Lupus Affects Emotional, Mental Well-Being of Patients

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Most patients report not having participated in a lupus clinical trial, despite interest
The first treatment has been approved for children with systemic lupus erythematosus

FDA Approves First Treatment for Pediatric Lupus

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Approval based on study showing children who received Benlysta plus standard therapy had lower risk for flare
The microbiome of patients with systemic lupus erythematosus

Altered Gut Microbiome Seen in Patients With Active Lupus

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Patients with lupus had fivefold greater representation of Ruminococcus gnavus
For patients with end-stage renal disease due to lupus nephritis

Renal Transplant Improves Survival in ESRD Due to Lupus

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Survival benefit noted especially for cardiovascular disease in end-stage renal disease due to lupus nephritis

The American College of Rheumatology, Oct. 19-24

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The 82nd Annual Meeting of the American College of Rheumatology The annual meeting of the American College of Rheumatology was...
Systemic lupus erythematous is among the top 20 leading causes of death in females between the ages of 5 and 64 years in the United States

Lupus Is a Leading Cause of Death in Young Women

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Death from lupus ranked 10th in women 15 to 24 years, 14th in those aged 25 to 34 and 35 to 44 years
Weekly belimumab is associated with greater benefit than placebo for patients with hypocomplementemic/anti-double stranded DNA-positive systemic lupus erythematosus

Belimumab Aids Anti-dsDNA+, Hypocomplementemic Lupus

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More SLE Responder Index responders at week 52 in the belimumab group versus the placebo group