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Patients with systemic lupus erythematosus have increased colonization with Staphylococcus aureus in cutaneous lupus erythematosus lesions

S. aureus Colonization Increased in Skin Lesions in Lupus Patients

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Repression of barrier gene expression, increased S. aureus-binding integrins in SLE keratinocytes found
Peripheral nervous system disease is a component of systemic lupus erythematosus disease activity and has a significant negative impact on health-related quality of life

Peripheral Nervous System Events Not Common in Lupus

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History of neuropathy, older age at diagnosis among factors tied to longer time to resolution of PNS events
For patients with systemic lupus erythematosus

Anifrolumab Improves Response at 52 Weeks in Lupus

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Rate of composite response showing reduced disease activity higher with anifrolumab versus placebo
Hydroxychloroquine blood levels are useful in predicting retinopathy among patients with systemic lupus erythematosus

Hydroxychloroquine Blood Levels Predict Retinopathy Risk in Lupus

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Prospective cohort study demonstrates link between HCQ blood levels and retinopathy risk
Patients with systemic lupus erythematosus (SLE) are more likely to use opioids than persons without SLE

Many Systemic Lupus Erythematosus Patients Use Opioids

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Among SLE patients, likelihood of prescription opioids up for those using emergency department
In-hospital maternal mortality decreased from 1998 to 2015 in systemic lupus erythematosus (SLE) and non-SLE pregnancies

In-Hospital Maternal Mortality Down in Pregnancies With Lupus

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Mortality decrease greater in systemic lupus erythematosus pregnancies than in non-SLE pregnancies
Clinical manifestations of systemic lupus erythematosus vary by racial and ethnic groups

Lupus Manifestations Appear to Differ by Race, Ethnicity

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Increased risk for severe manifestations seen among blacks, Hispanics, and Asians/Pacific Islanders
Mortality from systemic lupus erythematosus is significantly higher among blacks

CDC: Racial Disparity Seen With Lupus-Related Deaths

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Deaths among blacks occur sooner after diagnosis and at younger age compared with whites
Adverse childhood experiences are associated with worse patient-reported systemic lupus erythematosus outcomes

Adverse Childhood Experiences Linked to Worse Lupus Outcomes

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More adverse childhood experiences associated with depression, poor overall health for those with SLE
More than 60 percent of patients with lupus report that the disease has a large effect on their emotional and mental well-being

Lupus Affects Emotional, Mental Well-Being of Patients

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Most patients report not having participated in a lupus clinical trial, despite interest