Tag: Lupus
Voclosporin Safe, Effective for Long-Term Treatment of Lupus Nephritis
Benefits include maintenance of urine protein creatinine ratio reductions, preserved kidney function
Fetal, Maternal Morbidity Increased for Patients With Lupus
Increased risk seen for fetal morbidity, including IUGR and preterm delivery, compared with patients without SLE
Lupus, RA Tied to Higher Risk for Adverse Obstetric, Birth Outcomes
Women with RA/SLE more often required hospitalization postpartum; infants of women with RA/SLE had more frequent rehospitalizations in first year of life
ACR: Long-Term Safety Demonstrated for Anifrolumab in Lupus
Exposure-adjusted incidence rates of serious adverse events 8.5 versus 11.2 per 100 patient-years for anifrolumab versus placebo
ACR: Low-Dose Hydroxychloroquine Tied to More Hospitalizations for Lupus Flares
Both weight-based and non-weight-based low-dose HCQ associated with increased hospitalizations for SLE
Sleep Deprivation May Increase Risk for Systemic Lupus in Women
Additive interactions between low sleep duration and depression or bodily pain may contribute to risk for systemic lupus erythematosus
Reduction in Swollen, Tender Joints Greater With Litifilimab in Lupus
Most secondary end points did not support the results of the analysis for the primary end point
Breakthrough Infections in Lupus Patients Down With COVID Booster
Sixty-four percent of those with breakthrough COVID-19 had received booster compared with 82 percent of those without breakthrough infection
Normal-Looking Skin Involved in Cutaneous Lupus Erythematosus
Normal-appearing skin is type I interferon-rich environment; interferon-induced gene expression changes seen in all major skin type cells
Racial Disparities Seen in Adverse Renal Outcomes for Pediatric Lupus
Proportion of admissions with adverse renal outcomes decreased from 2006 to 2019, but racial disparities persisted
