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Tag: Liver Disease: Misc.

Sarcopenia Worsens Liver Transplant Outcomes for Patients With Cirrhosis

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Sarcopenia tied to longer intensive care unit stay, more major complications, higher postoperative mortality

Hepatitis C Virus Still Leading Cause of Hepatocellular Cancer in Men

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Since 2017, leading cause of HCC is NAFLD among women; increases in ALD- and NAFLD-HCC seen since 2015

Rates of Tx Retention for Rifaximin Low Despite Benefits for Hepatic Encephalopathy

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Lower treatment retention rates seen with 30-day, out-of-pocket costs ≥$150

Technical Variant Graft Usage Affects Pediatric Liver Transplant Waitlist Mortality

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Higher technical variant graft usage from living or deceased donor linked to lower waitlist mortality in pediatric liver transplant candidates

Recommendations Developed for Management of Acute Liver Failure

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Comprehensive testing is essential to elucidate diagnosis and exclude underlying chronic liver disease

Bulevirtide Linked to Decline in Hepatitis D Virus RNA Levels

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Normalization of alanine aminotransferase also seen with bulevirtide 2- or 10-mg

Pegozafermin Leads to Improvements in Fibrosis in NASH

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Improvements also seen in NASH resolution with pegozafermin 15 or 30 mg weekly, or 44 mg every two weeks

Novel Dialysis Device Safe, Effective for Acute-on-Chronic Liver Failure

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No difference seen in 28-day mortality or occurrence of serious adverse events; time to resolution of ACLF significantly faster

Liver Function Tests Can ID Occult Disorders in Systemic Sclerosis

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Predictors of abnormal liver function test include elderly onset of SSc, alcoholic drinking, and edematous skin

Advanced Liver Disease Up With Heavy Alcohol Use With, Without Metabolic Syndrome

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Absolute change in advanced liver disease highest in heavy alcohol use subgroups with and without MetS