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Tag: Liver Disease: Misc.

Chinese herbal medicine and Western medicine have different effects as causes of drug-induced liver injury

Drug-Induced Liver Injury From Chinese, Western Meds Varies

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Cases caused by Chinese herbal medicine have more hepatocellular injury and higher mortality
Regular coffee consumption seems to delay disease progression in alcoholic liver disease and primary sclerosing cholangitis patients with end-stage liver disease and increase long-term survival following liver transplantation

Drinking Coffee May Slow Progression of Liver Disease

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Appears to delay disease progression and increase post-transplantation survival
Curcumin exerts a hepatoprotective effect against acetaminophen-induced damage in mice

Curcumin May Help Prevent Liver Damage From Acetaminophen

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Effect seen in histological, plasma analysis by preventing mitochondrial changes
For obese patients with type 2 diabetes mellitus

NAFLD Linked to Unfavorable Metabolic Profile in T2DM

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More severe hyperinsulinemia, dyslipidemia, and adipose tissue/hepatic insulin resistance with NAFLD
Zepatier (elbasvir and grazoprevir) has been approved by the U.S. Food and Drug Administration to treat chronic hepatitis C virus genotypes 1 and 4 infections.

FDA Approves Zepatier for Chronic Hepatitis C

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Medication indicated for patients with hepatitis C virus genotypes 1 and 4 infections
Curcumin can attenuate acetaminophen-induced mitochondrial alterations in the livers of mice

Curcumin Cuts Acetaminophen-Induced Hepatotoxicity in Mice

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Protective effect of curcumin linked to attenuation of mitochondrial dysfunction
Chronic drinking combined with binge drinking may be more destructive than previously thought

Alcohol Binge Damage May Be Worse Than Previously Thought

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Per experimental study of chronic alcohol use combined with frequent binges
For patients with chronic hepatitis C virus (HCV)

AFP Levels Predict Fibrosis Regression After SVR in Hep C

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Lower α-fetoprotein, HCV type 2 tied to liver fibrosis regression after sustained virological response
In the United States

Burden, Costs of Gastrointestinal, Liver Disease Estimated in U.S.

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GI hemorrhage is most common diagnosis leading to hospitalization, with cost of $5 billion in 2012
For patients without diabetes with ST-segment myocardial infarction treated with primary percutaneous coronary intervention

Nonalcoholic Fatty Liver Disease Predicts MACE in STEMI

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Patients with moderate to severe fatty liver disease more likely to have impaired myocardial infusion