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Tag: Liver Disease: Misc.

The combination drug Epclusa has been approved by the U.S. Food and Drug Administration to treat the six major strains of chronic hepatitis C virus.

FDA Approves Epclusa for Chronic Hepatitis C

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Combination drug treats six major strains of hepatitis C virus infection
Alanine aminotransferase levels within normal range are associated with cardiovascular event risk

ALT Levels Within Normal Range Linked to Cardiovascular Events

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Incident cardiovascular events were highest for those in the lowest tertile of baseline ALT
For patients with prediabetes or type 2 diabetes mellitus and nonalcoholic steatohepatitis

Long-Term Pioglitazone Safe, Effective for NASH, T2DM

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Safe and effective for patients with prediabetes or type 2 diabetes and nonalcoholic steatohepatitis
Older teen boys who are overweight or obese could be at increased risk for severe liver disease later in life

Obesity in Older Male Teens Ups Risk for Liver Disease Later

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Researchers find odds increase as weight goes up
Ocaliva (obeticholic acid) has been approved by the U.S. Food and Drug Administration to treat primary biliary cholangitis in combination with ursodeoxycholic acid (UDCA) in adults with inadequate response to UDCA

FDA Approves Ocaliva for Primary Biliary Cholangitis

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For patients who have not responded to, or cannot tolerate, ursodeoxycholic acid
For patients with compensated hepatitis C virus cirrhosis

Survival for HCV Cirrhosis, SVR Same As General Population

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Findings in patients with compensated HCV cirrhosis who achieve SVR on interferon-based regimen
A first case of paintball-related blunt liver injury has been described in an article published online April 27 in BMJ Case Reports.

First Case of Paintball-Linked Liver Injury Described

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18-year-old male presented with symptoms consistent with acute appendicitis
In liver transplantation

First-Degree Relative Grafts Don’t Up Liver Disease Recurrence

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No difference in autoimmune recurrence, liver graft, or patient survival using first-degree donors
Hepatitis C virus (HCV)-infected livers seem to do as well as healthy livers in patients with HCV

HCV-Infected Liver Transplants Can Work for HCV+ Patients

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Findings might help reduce organ waiting list, researchers say
Steatosis affects more than half of liver transplant recipients

Steatosis in More Than Half of Liver Transplant Recipients

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Risk of significant steatosis affected by pre- and post-transplant factors, initial immunosuppression