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Home Tags Liver Disease: Misc.

Tag: Liver Disease: Misc.

Among children with non-alcoholic fatty liver disease

Uric Acid Concentration, Fructose Intake Up NASH in Children

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Independent associations seen in cohort of obese children with non-alcoholic fatty liver disease
Human pregnancy hormone chorionic gonadotropin triggers immune suppression by attenuating the processing and release of Caspase-3-dependent interleukin-16

hCG Reduces Caspase-3-Dependent IL-16 Expression

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Absence of Caspase-3 activity results in reduction of processing and release of interleukin-16
For patients with chronic kidney disease

Metformin Tied to Better Clinical Outcomes in CKD, CHF, CLD

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Reduced all-cause death for chronic kidney disease, congestive heart failure, chronic liver disease
Liver transplantation patients should undergo addiction consultation to accurately detect alcohol consumption

Addiction Consultation Valuable for Liver Transplant Patients

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Increased alcohol consumption identified in interviews with addiction specialists vs hepatologists
Evidence-based recommendations have been developed for screening

Recommendations Developed for Pediatric NAFLD

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Recommendations relate to screening, diagnosis, treatment, and long-term care of pediatric NAFLD
For patients with nonalcoholic steatohepatitis

Bariatric Surgery Effective, Cost-Effective in Obese With NASH

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For overweight patients, surgery is effective, but cost-effectiveness limited to those with F3 fibrosis
For hepatitis C virus (HCV) patients with decompensated cirrhosis who are eligible for liver transplant

Optimal MELD Threshold for HCV Tx Pre-Liver Transplant 23 to 27

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Treating HCV before liver transplant increased life expectancy if MELD was ≤27
Herbal and dietary supplement-induced liver injury accounts for 20 percent of cases of hepatotoxicity in the United States

Herbal, Dietary Supplements Cause One-Fifth of Hepatotoxicity

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Major implicated agents include anabolic steroids, green tea, multi-ingredient nutritional supplements
For patients with chronic hepatitis B

Liver Stiffness Linked to Hepatic Events, Death in Hepatitis B

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Metabolic syndrome ups risk of cardiovascular events, not hepatic events or death in chronic hep B
From 2001 to 2011 there was a considerable increase in the burden of cirrhosis and acute-on-chronic liver failure

Burden of Cirrhosis, Acute-on-Chronic Liver Failure Increasing

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From 2001 to 2011, number of hospitalizations for cirrhosis nearly doubled; prevalence of ACLF up