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Home Tags Liver Disease: Misc.

Tag: Liver Disease: Misc.

Doptelet (avatrombopag) has been approved by the U.S. Food and Drug Administration to treat adults with chronic liver disease who are slated to have a medical or dental procedure.

FDA OKs Doptelet for Liver Dz Patients Undergoing Procedures

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Doptelet reduces the need for platelet transfusion or any rescue therapy on day of procedure
Ethnicity/race

Factors ID’d to Predict Fatty Liver in Obese Teens

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African-American obese teens more susceptible to fatty liver effects on glucose metabolism
Increased adiposity in childhood may negatively impact liver function in children as young as 8 years old

Obesity Can Negatively Effect Liver in Children As Young As 8

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At mid-childhood, 23 percent of studied children with high waist circumference had elevated ALT
Mobile alcohol interventions may help liver transplant candidates with alcoholic liver disease maintain sobriety

Text Message-Based Intervention Helps With Sobriety Maintenance

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Findings among liver transplant candidates with alcoholic liver disease
Alternatives to whole liver transplants for children have become safer

Alternatives to Whole Liver Transplants Feasible for Children

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Alternatives helped to improve outcomes 2002 to 2015, indicating new ways to increase organ supply
Hepatic fat accumulation may play a causal role in chronic liver disease

Hepatic Fat Accumulation May Have Causal Role in Liver Disease

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Impact of genetic variants on liver damage proportional to effect on hepatic fat accumulation
Liver transplantation in childhood is associated with good long-term survival

Good Long-Term Survival After Childhood Liver Transplant

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20-year survival almost 80 percent; over one-third of patients have CKD, altered liver biochemistries
Nonalcoholic fatty liver disease is not associated with increased risk of incident reflux esophagitis after adjustment for variables

NAFLD Not Independently Tied to Risk of Reflux Esophagitis

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After adjustment for BMI and other metabolic factors the association disappeared
Metabolic risk factors are associated with severe liver disease

Metabolic Risk Factors Linked to Severe Liver Disease

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Diabetes only significant predictor among alcohol risk users; alcohol use predictive for non-risk drinkers
Higher early childhood intake of alpha-tocopherol is associated with lower odds of elevated mid-childhood alanine aminotransferase levels

Vitamin E in Early Childhood Tied to Lower ALT Levels Later

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Findings persist when early diet considered; strengthened when BMI z-score taken into account