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Home Tags Liver Disease: Misc.

Tag: Liver Disease: Misc.

For patients with nonalcoholic fatty liver disease

Modest Alcohol Consumption May Reduce Mortality in NAFLD

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But drinking ≥1.5 drinks/day linked to increased mortality after adjustment for multiple confounders
Liver disease-related deaths

Liver Disease-Related Deaths Up Sharply From 1999 to 2016

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Adults aged 25 to 34 show greatest relative increase in mortality, driven by alcoholic cirrhosis
Nearly one-third of patients with primary biliary cholangitis who had had an inadequate response to ursodeoxycholic acid alone achieved a complete biochemical response with the addition of bezafibrate to treatment

Addition of Bezafibrate Beneficial in Primary Biliary Cholangitis

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Complete biochemical response in 31 percent of patients unresponsive to ursodeoxycholic acid alone
The health care costs associated with nonalcoholic fatty liver disease are considerable

High Costs for Diagnosis, Care of Nonalcoholic Fatty Liver Disease

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Costs were significantly higher than total annual costs per matched control with similar comorbidities
Doptelet (avatrombopag) has been approved by the U.S. Food and Drug Administration to treat adults with chronic liver disease who are slated to have a medical or dental procedure.

FDA OKs Doptelet for Liver Dz Patients Undergoing Procedures

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Doptelet reduces the need for platelet transfusion or any rescue therapy on day of procedure
Ethnicity/race

Factors ID’d to Predict Fatty Liver in Obese Teens

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African-American obese teens more susceptible to fatty liver effects on glucose metabolism
Increased adiposity in childhood may negatively impact liver function in children as young as 8 years old

Obesity Can Negatively Effect Liver in Children As Young As 8

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At mid-childhood, 23 percent of studied children with high waist circumference had elevated ALT
Mobile alcohol interventions may help liver transplant candidates with alcoholic liver disease maintain sobriety

Text Message-Based Intervention Helps With Sobriety Maintenance

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Findings among liver transplant candidates with alcoholic liver disease
Alternatives to whole liver transplants for children have become safer

Alternatives to Whole Liver Transplants Feasible for Children

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Alternatives helped to improve outcomes 2002 to 2015, indicating new ways to increase organ supply
Hepatic fat accumulation may play a causal role in chronic liver disease

Hepatic Fat Accumulation May Have Causal Role in Liver Disease

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Impact of genetic variants on liver damage proportional to effect on hepatic fat accumulation